Evidence map›Paper›PMID 19055357›Full record

ArticleTissue engineering. Part C, Methods2008

Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective.

Julia Gorelik, Nadire N Ali, Siti H Sheikh Abdul Kadir, Max Lab, Petra Stojkovic, Lyle Armstrong, Elena V Sviderskaya, Yuri A Negulyaev, David Klenerman, Dorothy C Bennett and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Tissue engineering. Part C, Methods, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Scanning Ion Conductance Microscopy.Chemical reviews · 2021
    Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Julia GorelikNational Heart and Lung Institute, Imperial College London, London, United Kingdom. j.gorelik@imperial.ac.uk
Nadire N Ali
Siti H Sheikh Abdul Kadir
Max Lab
Petra Stojkovic
Lyle Armstrong
Elena V Sviderskaya
Yuri A Negulyaev
David Klenerman
Dorothy C Bennett
Majlinda Lako
Sian E Harding
Miodrag Stojkovic
Yuri E Korchev
Imperial College London · GBCentre for Life · GBSt George's, University of London · GBFaculty (United Kingdom) · GBRussian Academy of Sciences · RUUniversity of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research Council BB/D018595/1Biotechnology and Biological Sciences Research Council BB/D020875/1Biotechnology and Biological Sciences Research Council C19021Medical Research Council G0301182Wellcome Trust 078310
6 · The paper itself

Abstract

The most valuable property of stem cells (SCs) is their potential to differentiate into many or all cell types of the body. So far, monitoring SC differentiation has only been possible after cells were fixed or destroyed during sample preparation. It is, however, important to develop nondestructive methods of monitoring SCs. Scanning ion conductance microscopy (SICM) is a unique imaging technique that uses similar principles to the atomic force microscope, but with a pipette for the probe. This allows scanning of the surface of living cells noninvasively and enables measurement of cellular activities under more physiological conditions than is possible with other high-resolution microscopy techniques. We report here the novel use of the SICM for studying SCs to assess and monitor the status of SCs and various cell types differentiated from SCs.

Indexed as

AnimalsCell DifferentiationCell LineCell ProliferationEquipment DesignHumansMiceMicroscopy, ConfocalMicroscopy, Electron, ScanningNeural CrestNeuronsPatch-Clamp TechniquesReverse Transcriptase Polymerase Chain ReactionStem CellsSurface Properties

Identifiers

PMID19055357
PMCPMC2645517
OpenAlexW2015376874

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.