Evidence map›Paper›PMID 19054817›Full record

SynthesisAnnals of the rheumatic diseases2009

Efficacy and safety of steroid injections for shoulder and elbow tendonitis: a meta-analysis of randomised controlled trials.

C Gaujoux-Viala, M Dougados, L Gossec

3 registry-linked trialsOpen access · hybridAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Annals of the rheumatic diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 69 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 6 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01402011 nacompletednot on this mapstarted 2010, after this paper: background citation

Rotator Cuff Tendinopathy: A Randomized and Blinded Comparison of Superficial and Deep Injection Methods

TypeinterventionalSponsorUniversity of British ColumbiaRan2010 to 2013Enrolled77ConditionsRotator Cuff TendinitisArms25% dextrose in shoulder entheses, .1% lidocaine in shoulder entheses, .1% lidocaine subcu. above shouldr enth.
NCT03586687 phase4terminatednot on this mapstarted 2018, after this paper: background citation

Clinical Outcomes Following Randomization of Steroid Concentration in Patients With Glenohumeral Osteoarthritis

TypeinterventionalSponsorMilton S. Hershey Medical CenterRan2018 to 2021Enrolled19ConditionsGlenohumeral OsteoarthritisArmsTriamcinolone
NCT04094298 phase3active not recruitingnot on this mapstarted 2019, after this paper: background citation

Use of Extended Release Triamcinolone in the Treatment of Rotator Cuff Disease

TypeinterventionalSponsorNorthwell HealthRan2019 to 2025Enrolled65ConditionsRotator Cuff Tears, Rotator Cuff Tendinitis, Rotator Cuff Impingement, InjectionsArmsFX006 Injection
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 6 syntheses or guidelines pooled it, 197 citations in OpenAlex.

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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

C Gaujoux-VialaParis Descartes University, Medicine Faculty, UPRES-EA 4058, APHP, Rheumatology B Department, Cochin Hospital, 75014 Paris, France. cecilegaujouxviala@yahoo.fr
M Dougados
L Gossec
Délégation Paris 5 · FRDescartes (Belgium) · BEHôpital Cochin · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the efficacy and safety of steroid injections for patients with tendonitis of the shoulder or elbow.

methodsA systematic review of the literature using PubMed, EMBASE, the Cochrane library and manual searches was performed until April 2008. All randomised controlled trials (RCTs) reporting the efficacy on pain or functional disability, and/or the safety of steroid injections, versus placebo, non-steroidal anti-inflammatory drugs (NSAIDs) or physiotherapy in patients with tendonitis were selected. Pooled effect size (ES) was calculated by meta-analysis using the Mantel-Haenszel method.

resultsIn all, 20 RCTs were analysed (744 patients treated by injections and 987 patients treated by controls; 618 shoulders and 1113 elbows). The pooled analysis indicated only short-term effectiveness of steroids versus the pooled controls for pain and function (eg, pain at week 1-3 ES = 1.18 (95% CI 0.27 to 2.09), pain at week 4-8 ES = 1.30 (95% CI 0.55 to 2.04), pain at week 12-24 ES = -0.38 (95% CI -0.85 to 0.08) and pain at week 48 ES = 0.07 (95% CI -0.60 to 0.75)). Sensitivity analyses indicated similar results whatever the localisation, type of steroid and type of comparator except for NSAIDs: steroid injections were not significantly better than NSAIDs in the short-term. Steroid injections appeared more effective than pooled other treatments in acute or subacute tendonitis. The main side effects were transient pain after injection (10.7% of corticosteroid injections) and skin modification (4.0%).

conclusionsSteroid injections are well tolerated and more effective for tendonitis in the short-term than pooled other treatments, though similar to NSAIDs. No long-term benefit was shown.

Indexed as

Elbow JointShoulder JointAdultFemaleGlucocorticoidsHumansInjections, Intra-ArticularMaleMiddle AgedRandomized Controlled Trials as TopicSensitivity and SpecificityTendinopathyTreatment OutcomeGlucocorticoids

Identifiers

PMID19054817
PMCPMC2770107
OpenAlexW2170697272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.