ArticleAtencion primaria2008
[Validation of a rapid antigenic test in the diagnosis of pharyngitis caused by group a beta-haemolytic Streptococcus].
Article in Atencion primaria, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Rapid antigen detection test for group A streptococcus in children with pharyngitis.The Cochrane database of systematic reviews · 2016Pooled it
- Rapid antigen group A streptococcus test to diagnose pharyngitis: a systematic review and meta-analysis.PloS one · 2014Pooled it
- Predicting streptococcal pharyngitis in adults in primary care: a systematic review of the diagnostic accuracy of symptoms and signs and validation of the Centor score.BMC medicine · 2011Pooled it
- [Introduction of rapid streptococcal antigen test: can its use improve adherence to antibiotic therapy?]Atencion primaria · 2021Trial
- The use of rapid tests beyond established clinical recommendations should be avoided entirely.Scandinavian journal of primary health care · 2025Article
- Article
- [Recommendations for management of acute pharyngitis in adults].Enfermedades infecciosas y microbiologia clinica · 2016Review
- Review
- [Recommendations for management of acute pharyngitis in adults].Atencion primaria · 2015Article
- [Validation Analyz-Strep A Rapid Test in the diagnosis of acute pharyngitis].Atencion primaria · 2015Article
- Diagnosis and management of acute pharyngitis in a paediatric population: a cost-effectiveness analysis.European journal of pediatrics · 2011Article
- [Does a pharyngeal culture have to be requested when using rapid antigen techniques?].Atencion primaria · 2010Article
- [Early diagnosis of streptococcal pharyngitis in paediatric practice: Validity of a rapid antigen detection test].Atencion primaria · 2010Article
- [Rapid antigen tests for beta-haemolytic streptococcus in primary care].Atencion primaria · 2009Article
- Recommendations for management of acute pharyngitis in adults.Acta otorrinolaringologica espanolaReview
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the validity of the rapid antigen test (RAT) OSOM StrepA Genzyme for the diagnosis of acute pharyngitis caused by group A beta-haemolytic strep (GABHS).
designDiagnostic techniques survey.
settingUrban primary care centre, Spain.
participantsAll patients over 14 years old seen in 6 surgeries with sore throat and 2 or more Centor criteria: pharyngotonsillar exudate, tender laterocervical nodes, absence of coughing, and/or history or presence of fever. PRINCIPAL MEASUREMENTS: Pharyngeal swabs were taken from all the patients, one for RAT and another to send for culture in the microbiology department.
resultsA total of 182 patients were evaluable, with a mean age of 30.6 (12.1) years of which 116 were women (63.7%); 63 patients had 2 Centor criteria; 83 had 3 and 36, the 4 criteria. The culture was positive in 102 patients (56%), with GABHS showing infection in forty (22%; 95% confidence interval [CI], 21.2-22.8). Group C Streptococcus was isolated in 26 patients (14.3%). GABHS was higher among patients with four Centor criteria (38.9% vs 25.3% observed among those with 3 criteria and 7.9% with 2 criteria; P<.001). Sensitivity of RAT was 95%, with a specificity of 93%, a positive predictive value of 79.2% and a negative predictive value of 98.5%.
conclusionsThese results show the usefulness of RAT for diagnosing streptococcal pharyngitis. Its use should be spread to all primary care practices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.