Evidence map›Paper›PMID 19052047›Full record

Trial reportThorax2009

Breathing exercises for asthma: a randomised controlled trial.

M Thomas, R K McKinley, S Mellor, G Watkin, E Holloway, J Scullion, D E Shaw, A Wardlaw, D Price, I Pavord

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Thorax, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 4 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 159 citations in OpenAlex.

  1. Pooled it
  2. Breathing exercises for adults with asthma.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Breathing exercises for children with asthma.The Cochrane database of systematic reviews · 2016
    Pooled it
  4. Psychosocial factors and behavioral medicine interventions in asthma.Journal of consulting and clinical psychology · 2013
    Pooled it
  5. Trial
  6. Impact of interventions targeting anxiety and depression in adults with asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022
    Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. The BREATHE study: Breathing REtraining for Asthma--Trial of Home Exercises. a protocol summary of a randomised controlled trial.Primary care respiratory journal : journal of the General Practice Airways Group · 2013
    Trial
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Effects of Exercise on COVID-19 Patients: A Narrative Review.Medical journal of the Islamic Republic of Iran · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

M ThomasDepartment of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Aberdeen, UK. mikethomas@doctors.org.uk
R K McKinley
S Mellor
G Watkin
E Holloway
J Scullion
D E Shaw
A Wardlaw
D Price
I Pavord
Glenfield Hospital · GBKeele University · GBUniversity College London · GBUniversity of Aberdeen · GBUniversity of Science and Technology Chittagong · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effect of breathing modification techniques on asthma symptoms and objective disease control is uncertain.

methodsA prospective, parallel group, single-blind, randomised controlled trial comparing breathing training with asthma education (to control for non-specific effects of clinician attention) was performed. Subjects with asthma with impaired health status managed in primary care were randomised to receive three sessions of either physiotherapist-supervised breathing training (n = 94) or asthma nurse-delivered asthma education (n = 89). The main outcome was Asthma Quality of Life Questionnaire (AQLQ) score, with secondary outcomes including spirometry, bronchial hyper-responsiveness, exhaled nitric oxide, induced sputum eosinophil count and Asthma Control Questionnaire (ACQ), Hospital Anxiety and Depression (HAD) and hyperventilation (Nijmegen) questionnaire scores.

resultsOne month after the intervention there were similar improvements in AQLQ scores from baseline in both groups but at 6 months there was a significant between-group difference favouring breathing training (0.38 units, 95% CI 0.08 to 0.68). At the 6-month assessment there were significant between-group differences favouring breathing training in HAD anxiety (1.1, 95% CI 0.2 to 1.9), HAD depression (0.8, 95% CI 0.1 to 1.4) and Nijmegen (3.2, 95% CI 1.0 to 5.4) scores, with trends to improved ACQ (0.2, 95% CI 0.0 to 0.4). No significant between-group differences were seen at 1 month. Breathing training was not associated with significant changes in airways physiology, inflammation or hyper-responsiveness.

conclusionBreathing training resulted in improvements in asthma-specific health status and other patient-centred measures but not in asthma pathophysiology. Such exercises may help patients whose quality of life is impaired by asthma, but they are unlikely to reduce the need for anti-inflammatory medication.

Indexed as

Breathing ExercisesAdultAgedAsthmaBronchoconstrictor AgentsFemaleForced Expiratory VolumeHumansHyperventilationMaleMethacholine ChlorideMiddle AgedNitric OxideQuality of LifeSingle-Blind MethodSputumBronchoconstrictor AgentsMethacholine ChlorideNitric Oxide

Identifiers

PMID19052047
OpenAlexW2142045931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.