Evidence map›Paper›PMID 19051126›Full record

ReviewStress (Amsterdam, Netherlands)2009

Glucocorticoid receptor dynamics and gene regulation.

Simon C Biddie, Gordon L Hager

Open access · bronzeAbstract readReview
In one paragraph

Review in Stress (Amsterdam, Netherlands), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 71 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Abiotic stressors in poultry production: A comprehensive review.Journal of animal physiology and animal nutrition · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Simon C BiddieLaboratory of Receptor Biology and Gene Expression, National Cancer Institute, NIH, Bethesda, MD 20892-5055, USA.
Gordon L Hager
National Cancer Institute · USNational Institutes of Health · US

Funding

Chromatin Structure and Gene ExpressionZIABC005450 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HAGER, GORDON L · 2009 to 2025
$35.2M
Function of Steroid Receptors in Subcellular CompartmentsZIABC010027 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HAGER, GORDON L · 2009 to 2025
$8.7M
CHROMATIN STRUCTURE AND GENE EXPRESSIONZ01BC005450 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HAGER, GORDON · 1996 to 2008
$1.7M
Intramural NIH HHS Z01 BC005450
6 · The paper itself

Abstract

The glucocorticoid receptor regulates the expression of a large number of genes in mammalian cells. The interaction of this receptor with regulatory elements has been discovered to be highly dynamic, with occupancy states measured in seconds, rather than minutes or hours. This finding has led to a paradigm shift in our understanding of receptor function throughout the genome. The mechanisms involved in these rapid exchange events, as well as the implications for receptor function, are discussed.

Indexed as

Adenosine TriphosphateAnimalsChromatin Assembly and DisassemblyDNA-Binding ProteinsGene Expression RegulationHumansMiceModels, GeneticMolecular ChaperonesPromoter Regions, GeneticProteasome Endopeptidase ComplexReceptors, GlucocorticoidAdenosine TriphosphateDNA-Binding ProteinsMNBP-1 protein, humanMolecular ChaperonesProteasome Endopeptidase ComplexReceptors, Glucocorticoid

Identifiers

PMID19051126
PMCPMC6319377
OpenAlexW2136912241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.