Evidence map›Paper›PMID 19050738›Full record

ArticleAtmospheric environment (Oxford, England : 1994)2007

Fungal Fragments in Moldy Houses: A Field Study in Homes in New Orleans and Southern Ohio.

Tiina Reponen, Sung-Chul Seo, Faye Grimsley, Taekhee Lee, Carlos Crawford, Sergey A Grinshpun

Abstract read
In one paragraph

Article in Atmospheric environment (Oxford, England : 1994), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Direct-Read Fluorescence-Based Measurements of Bioaerosol Exposure in Home Healthcare.International journal of environmental research and public health · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Indoor mould exposure, asthma and rhinitis: findings from systematic reviews and recent longitudinal studies.European respiratory review : an official journal of the European Respiratory Society · 2018
    Review
  10. Fungal Fragments and Fungal Aerosol Composition in Sawmills.Annals of work exposures and health · 2018
    Article
  11. Mold and Human Health: a Reality Check.Clinical reviews in allergy & immunology · 2017
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Exposures to molds in school classrooms of children with asthma.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2013
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tiina ReponenDepartment of Environmental Health, University of Cincinnati, Cincinnati, OH.
Sung-Chul Seo
Faye Grimsley
Taekhee Lee
Carlos Crawford
Sergey A Grinshpun

Funding

REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY RESEARCHP30ES006096 · NIEHS · UNIVERSITY OF CINCINNATI · PI YADAV, JAGJIT S · 1992 to 2022
$35.4M
NIEHS NIH HHS P30 ES006096
6 · The paper itself

Abstract

Smaller-sized fungal fragments (<1 μm) may contribute to mold-related health effects. Previous laboratory-based studies have shown that the number concentration of fungal fragments can be up to 500 times higher than that of fungal spores, but this has not yet been confirmed in a field study due to lack of suitable methodology. We have recently developed a field-compatible method for the sampling and analysis of airborne fungal fragments. The new methodology was utilized for characterizing fungal fragment exposures in mold-contaminated homes selected in New Orleans, Louisiana and Southern Ohio. Airborne fungal particles were separated into three distinct size fractions: (i) >2.25 μm (spores); (ii) 1.05-2.25 μm (mixture); and (iii) < 1.0 μm (submicrometer-sized fragments). Samples were collected in five homes in summer and winter and analyzed for (1→3)-β-D-glucan. The total (1→3)-β-D-glucan varied from 0.2 to 16.0 ng m(-3). The ratio of (1→3)-β-D-glucan mass in fragment size fraction to that in spore size fraction (F/S) varied from 0.011 to 2.163. The mass ratio was higher in winter (average = 1.017) than in summer (0.227) coinciding with a lower relative humidity in the winter. Assuming a mass-based F/S-ratio=1 and the spore size = 3 μm, the corresponding number-based F/S-ratio (fragment number/spore number) would be 10(3) and 10(6), for the fragment sizes of 0.3 and 0.03 μm, respectively. These results indicate that the actual (field) contribution of fungal fragments to the overall exposure may be very high, even much greater than that estimated in our earlier laboratory-based studies.

Identifiers

PMID19050738
PMCPMC2153459

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.