ArticleProceedings of the National Academy of Sciences of the United States of America2008
A PIIB-type Ca2+-ATPase is essential for stress adaptation in Physcomitrella patens.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 43 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
43 citing papers in PubMed, 108 citations in OpenAlex.
- Nontoxic mesoporous silica nanoparticles protect Physcomitrium patens against salt stress.Stress biology · 2025Article
- Cellular calcium homeostasis and regulation of its dynamic perturbation.Quantitative plant biology · 2025Review
- OsACA9, an Autoinhibited CaInternational journal of molecular sciences · 2024Article
- Long-Distance Electrical and Calcium Signals Evoked by Hydrogen Peroxide in Physcomitrella.Plant & cell physiology · 2023Article
- Yeast Heterologous Expression Systems for the Study of Plant Membrane Proteins.International journal of molecular sciences · 2023Review
- CIPK-B is essential for salt stress signalling in Marchantia polymorpha.The New phytologist · 2023Article
- Transcriptome changes induced by Arbuscular mycorrhizal symbiosis in leaves of durum wheat (Triticum durum Desf.) promote higher salt tolerance.Scientific reports · 2023Article
- Evolutionary and Regulatory Pattern Analysis of Soybean CaFrontiers in plant science · 2022Article
- Calcium channels and transporters: Roles in response to biotic and abiotic stresses.Frontiers in plant science · 2022Review
- Delineating Calcium Signaling Machinery in Plants: Tapping the Potential through Functional Genomics.Current genomics · 2021Review
- The signatures of organellar calcium.Plant physiology · 2021Review
- Phytohormone biosynthesis and signaling pathways of mosses.Plant molecular biology · 2021Review
- Cellular Localization of Exogenous Cry1Ab/c and its Interaction with Plasma Membrane CaFrontiers in bioengineering and biotechnology · 2021Article
- Tonoplast-localized CaProceedings of the National Academy of Sciences of the United States of America · 2020Article
- ABA-Induced Vegetative Diaspore Formation inFrontiers in plant science · 2019Article
- Simultaneous imaging and functional studies reveal a tight correlation between calcium and actin networks.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Transcriptomic Profiling and Physiological Analysis of Haloxylon ammodendron in Response to Osmotic Stress.International journal of molecular sciences · 2017Article
- Genetically encoded calcium indicators for fluorescence imaging in the moss Physcomitrella: GCaMP3 provides a bright new look.Plant biotechnology journal · 2017Article
- Calcium Pumps and Interacting BON1 Protein Modulate Calcium Signature, Stomatal Closure, and Plant Immunity.Plant physiology · 2017Article
- Ca2+-dependent phosphoregulation of the plasma membrane Ca2+-ATPase ACA8 modulates stimulus-induced calcium signatures.Journal of experimental botany · 2017Article
Corrections and comments
- Commented on by
- Erratum issuedHoltorf, Hauke [added]
Authors and funding
8 authors at 4 institutions in 5 countries.
Funding
Abstract
Transient cytosolic Ca(2+) ([Ca(2+)](cyt)) elevations are early events in plant signaling pathways including those related to abiotic stress. The restoration of [Ca(2+)](cyt) to prestimulus levels involves ATP-driven Ca(2+) pumps, but direct evidence for an essential role of a plant Ca(2+)-ATPase in abiotic stress adaptation is missing. Here, we report on a stress-responsive Ca(2+)-ATPase gene (PCA1) from the moss Physcomitrella patens. Functional analysis of PCA1 in a Ca(2+) transport-deficient yeast mutant suggests that PCA1 encodes a P(IIB)-type Ca(2+)-ATPase harboring an N-terminal autoinhibitory domain. In vivo localizations identified membranes of small vacuoles as the integration site for a PCA1:GFP fusion protein. PCA1 mRNA levels are up-regulated by dehydration, NaCl, and abscisic acid, and PCA1 loss-of-function mutants (DeltaPCA1) exhibit an enhanced susceptibility to salt stress. The DeltaPCA1 lines show sustained elevated [Ca(2+)](cyt) in response to salt treatment in contrast to WT that shows transient Ca(2+) elevations, indicating a direct role for PCA1 in the restoration of prestimulus [Ca(2+)](cyt). The altered Ca(2+) response of the DeltaPCA1 mutant lines correlates with altered expression levels of stress-induced genes, suggesting disturbance of a stress-associated signaling pathway. We propose that PCA1 is an essential component for abiotic stress adaptation in Physcomitrella involved in the generation of a specific salt-induced Ca(2+) signature.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.