ArticleFetal diagnosis and therapy2008
Prenatal diagnosis of annular pancreas: reliability of the double bubble sign with periduodenal hyperechogenic band.
Article in Fetal diagnosis and therapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 41 citations in OpenAlex.
- Robotic versus laparoscopic approaches to neonatal annular pancreas: a comparative analysis of surgical outcomes and innovation trade-offs.Surgical endoscopy · 2025Article
- Clinical insights from a rare case of neonatal upper gastrointestinal obstruction complicated by H-Type tracheoesophageal fistula: case report and review of the literature.BMC pediatrics · 2025Review
- Clinical Analysis of Congenital Duodenal Obstruction and the Role of Annular Pancreas.Medicina (Kaunas, Lithuania) · 2025Article
- Annular pancreas: Radiological features of a rare case of infantile vomiting.Radiology case reports · 2022Article
- The value of saline-aided ultrasound in diagnosing congenital duodenal obstruction.Pediatric surgery international · 2020Article
- Diagnostic value of the acute angle between the prestenotic and poststenotic duodenum in neonatal annular pancreas.European radiology · 2019Article
- Laparoscopic diagnosis and treatment of neonates with duodenal obstruction associated with an annular pancreas: report of 11 cases.Surgery today · 2015Article
- Antenatally detected cystic biliary atresia: differential diagnoses of a double bubble.SpringerPlus · 2014Article
- Pseudo double bubble: jejunal duplication mimicking duodenal atresia on prenatal ultrasound.Journal of neonatal surgeryArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
Abstract
objectiveTo evaluate the power of prenatal 2-D ultrasound examination in the 2nd trimester as a method of choice for accurate diagnosis of annular pancreas.
methodsCo-incidence of the double bubble sign (often accompanying gastroduodenal dilatation) together with a hyperechogenic band around the duodenum (corresponding with the tissue of annular pancreas) was used as a diagnostic criterion. Findings from postnatal surgery served for verification.
resultsFrom 7,897 screened pregnancies, annular pancreas was proven in the cases where both signs were present, but never without the hyperechogenic band (N(1) = 3, N(2) = 3, p < or = 0.05). Sensitivity and specificity were 100%.
conclusionsMore multicentric studies are required to test this approach. The following diagnostic strategy is reasonable at the present time: when the double bubble sign is discovered, always suspect annular pancreas and look for the second sign: hyperechogenic bands around the duodenum. Also look for known associated anomalies, and vice versa, if any of associated anomalies are noted, also search specifically for the signs of annular pancreas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.