ArticleThe Journal of physiology2009
Excitatory and inhibitory intermediate zone interneurons in pathways from feline group I and II afferents: differences in axonal projections and input.
Article in The Journal of physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- Spatial and network principles behind neural generation of locomotion.Nature communications · 2026Article
- Neuronal mechanisms underlying activation of locomotor network by epidural electrical stimulation of the spinal cord.Experimental neurology · 2025Article
- Neuroanatomy of spinal nociception and pain in dogs and cats: a practical review for the veterinary clinician.Frontiers in veterinary science · 2025Review
- Latest Advancements in Transcutaneous Electrical Nerve Stimulation (TENS) and Electronic Muscle Stimulation (EMS): Revisiting an Established Therapy with New Possibilities.Journal of pain research · 2025Review
- Consecutive Transcutaneous and Epidural Spinal Cord Neuromodulation to Modify Clinical Complete Paralysis-the Proof of Concept.Mayo Clinic proceedings. Innovations, quality & outcomes · 2024Article
- Locomotor-related propriospinal V3 neurons produce primary afferent depolarization and modulate sensory transmission to motoneurons.Journal of neurophysiology · 2023Article
- Excitatory and Inhibitory Descending Commissural Interneurons Differentially Integrate Supraspinal and Segmental Sensory Signals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Deconstructing the modular organization and real-time dynamics of mammalian spinal locomotor networks.Nature communications · 2023Article
- The role of V3 neurons in speed-dependent interlimb coordination during locomotion in mice.eLife · 2022Article
- Discrete field potentials produced by coherent activation of spinal dorsal horn neurons.Experimental brain research · 2022Article
- A Re-evaluation of Whether Non-monosynaptic Homonymous H Reflex Facilitation Tests Propriospinal Circuits.Frontiers in systems neuroscience · 2021Article
- Long-latency Responses to a Mechanical Perturbation of the Index Finger Have a Spinal Component.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Rapid crossed responses in an intrinsic hand muscle during perturbed bimanual movements.Journal of neurophysiology · 2020Article
- The mammalian spinal commissural system: properties and functions.Journal of neurophysiology · 2020Review
- Afterdischarges of Spinal Interneurons Following a Brief High-Frequency Stimulation of Ia Afferents in the Cat.Frontiers in integrative neuroscience · 2019Article
- Changes in Activity of Spinal Postural Networks at Different Time Points After Spinalization.Frontiers in cellular neuroscience · 2019Article
- Distributed force feedback in the spinal cord and the regulation of limb mechanics.Journal of neurophysiology · 2018Review
- Convergence of ipsi- and contralateral muscle afferents on common interneurons mediating reciprocal inhibition of ankle plantarflexors in humans.Experimental brain research · 2017Article
- Effect of acute lateral hemisection of the spinal cord on spinal neurons of postural networks.Neuroscience · 2016Article
- Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb Position.Neuron · 2016Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The aim of the present study was to compare properties of excitatory and inhibitory spinal intermediate zone interneurons in pathways from group I and II muscle afferents in the cat. Interneurons were labelled intracellularly and their transmitter phenotypes were defined by using immunocytochemistry. In total 14 glutamatergic, 22 glycinergic and 2 GABAergic/glycinergic interneurons were retrieved. All interneurons were located in laminae V-VII of the L3-L7 segments. No consistent differences were found in the location, the soma sizes or the extent of the dendritic trees of excitatory and inhibitory interneurons. However, major differences were found in their axonal projections; excitatory interneurons projected either ipsilaterally, bilaterally or contralaterally, while inhibitory interneurons projected exclusively ipsilaterally. Terminal projections of glycinergic and glutamatergic cells were found within motor nuclei as well as other regions of the grey matter which include the intermediate region, laminae VII and VIII. Cells containing GABA/glycine had more restricted projections, principally within the intermediate zone where they formed appositions with glutamatergic axon terminals and unidentified cells and therefore are likely to be involved in presynaptic as well as postsynaptic inhibition. The majority of excitatory and inhibitory interneurons were found to be coexcited by group I and II afferents (monosynaptically) and by reticulospinal neurons (mono- or disynaptically) and to integrate information from several muscles. Taken together the morphological and electrophysiological data show that individual excitatory and inhibitory intermediate zone interneurons may operate in a highly differentiated way and thereby contribute to a variety of motor synergies.
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