Evidence map›Paper›PMID 19045958›Full record

ReviewBehavioral neuroscience2008

The state of the reward comparison hypothesis: theoretical comment on Huang and Hsiao (2008).

Patricia Sue Grigson

Abstract readReviewComment
In one paragraph

Review in Behavioral neuroscience, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Social interaction promotes nicotine self-administration with olfactogustatory cues in adolescent rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2011
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Patricia Sue GrigsonDepartment of Neural and Behavioral Sciences, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA. psg6@psu.edu

Funding

Drugs of Abuse and Learned Aversions: Solving a ParadoxR37DA009815 · NIDA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI GRIGSON, PATRICIA SUE · 2012 to 2020
$2.9M
DRUGS OF ABUSE, REWARD COMPARISON, AND THE THALAMUSR01DA012473 · NIDA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI GRIGSON, PATRICIA SUE · 2000 to 2010
$2.9M
DRUGS OF ABUSE AND LEARNED AVERSIONS: SOLVING A PARADOXR01DA009815 · NIDA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI GRIGSON, PATRICIA SUE · 1996 to 2011
$2.3M
NIDA NIH HHS DA09815NIDA NIH HHS DA12473NIDA NIH HHS R01 DA009815NIDA NIH HHS R01 DA012473NIDA NIH HHS R37 DA009815
6 · The paper itself

Abstract

Rats avoid intake of a gustatory cue following pairings with a drug of abuse, such as morphine or cocaine. Despite the well-established rewarding properties of these drugs, the reduction in intake of the taste cue has been interpreted as a conditioned taste aversion for decades. In 1997, I proposed the reward comparison hypothesis suggesting that rats avoided intake of the drug-associated taste cue because the value of the taste cue pales in comparison to the highly rewarding drug of abuse expected in the near future. In this issue of Behavioral Neuroscience, A. C. W. Huang and S. Hsiao challenge the reward comparison hypothesis by showing parallels between amphetamine and LiCl-induced suppression of CS intake. This commentary addresses the current state of the reward comparison hypothesis in the context of the experiments completed by Huang and Hsiao and their new task-dependent drug effects hypothesis.

Indexed as

Conditioning, PsychologicalPsychological TheoryRewardAnimalsAvoidance LearningBehavior, AnimalFood PreferencesHumans

Identifiers

PMID19045958
PMCPMC3684389

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.