Evidence map›Paper›PMID 19043779›Full record

ArticleMolecular and cellular biochemistry2009

Comparative evaluation of antioxidant reactivity within obstructed and control rabbit urinary bladder tissue using FRAP and CUPRAC assays.

Holly Bean, Florian Radu, Elise De, Catherine Schuler, Robert E Leggett, Robert M Levin

Abstract read
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In one paragraph

Article in Molecular and cellular biochemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Analytical Methods Used in Determining Antioxidant Activity: A Review.International journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Holly BeanAlbany College of Pharmacy, Stratton, NY, USA.
Florian Radu
Elise De
Catherine Schuler
Robert E Leggett
Robert M Levin
Albany College of Pharmacy and Health Sciences · USAlbany Medical Center Hospital · USAlbany Stratton VA Medical Center Albany · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Partial urinary bladder outlet obstruction mediates cyclic ischemia and reperfusion resulting in the generation of both reactive oxygen species and reactive nitrogen species. It is theorized that with an increase in the level of free radicals, the level of protective antioxidants should decrease. To test this hypothesis, two electron transfer assays, the FRAP method and the CUPRAC method, were used to determine the level of antioxidant reactivity of obstructed and control bladder tissue. The results showed that the CUPRAC assay detected a significant decrease in the reactivity of antioxidants found within the obstructed bladder tissue as compared to the control bladder tissue in both the muscle and mucosa. The FRAP assay did not detect any difference between the muscle and mucosa of the obstructed and control bladder tissue.

Indexed as

Fluorescence Recovery After PhotobleachingAnimalsAntioxidantsBiological AssayMaleMuscle, SmoothRabbitsReactive Nitrogen SpeciesReactive Oxygen SpeciesUrinary BladderUrinary Bladder Neck ObstructionAntioxidantsReactive Nitrogen SpeciesReactive Oxygen Species

Identifiers

PMID19043779
OpenAlexW1965888912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.