ArticleJournal of neuro-oncology2009
Anaplastic ganglioglioma in children.
Article in Journal of neuro-oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Natural history and neuro-oncological approach in spinal gangliogliomas: a systematic review.Neurosurgical review · 2024Pooled it
- Seizures in children with dysembryoplastic neuroepithelial tumors of the brain--A review of surgical outcomes across several studies.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Pooled it
- Anaplastic gangliogliomas of the spinal cord: a scoping review of the literature.Neurosurgical review · 2022Article
- Lentivirus vector‑mediated genetic manipulation of oncogenic pathways induces tumor formation in rabbit brain.Molecular medicine reports · 2021Article
- Low-grade gangliogliomas in adults: A population-based study.Cancer medicine · 2021Article
- Giant Cerebellar Ganglioglioma Mimicking a Pilocytic Astrocytoma.Journal of clinical imaging science · 2021Article
- Article
- H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components.Acta neuropathologica communications · 2019Article
- Impact of surgery, adjuvant treatment, and other prognostic factors in the management of anaplastic ganglioglioma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- A case of adult anaplastic cerebellar ganglioglioma.Surgical neurology international · 2018Article
- Natural course and prognosis of anaplastic gangliogliomas: a multicenter retrospective study of 43 cases from the French Brain Tumor Database.Neuro-oncology · 2017Article
- Pediatric intracranial primary anaplastic ganglioglioma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- Pediatric infratentorial ganglioglioma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Review
- Anaplastic ganglioglioma: a report of three cases and review of the literature.Journal of neuro-oncology · 2015Review
- Brainstem ganglioglioma in an infant: Case report and review of literature.Journal of pediatric neurosciences · 2013Article
- Long-term epilepsy-associated tumors.Brain pathology (Zurich, Switzerland) · 2012Review
- Pediatric high grade glioma of the spinal cord: results of the HIT-GBM database.Journal of neuro-oncology · 2012Article
- Outcome and prognostic features in anaplastic ganglioglioma: analysis of cases from the SEER database.Journal of neuro-oncology · 2011Article
- Malignant ganglioglioma: case report and review of literature.Journal of neuro-oncology · 2011Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAnaplastic gangliogliomas (AGG) are gangliogliomas with areas of pronounced hypercellularity, vascular proliferation, necrosis, and many mitotic figures. As very few pediatric patients have been studied, we analyzed the cases registered in the HIT-GBM database. PATIENTS AND
methodsPatient data were obtained from the German HIT-GBM database. Inclusion criteria were diagnosis of AGG proven by a central neuropathological review and patient age 0 to 17 years. Eight patients (five male and three female) were identified.
resultsPatients' median age was 10 years. The median history of disease was 9 months (range, 1.0-43.0 months). Initial symptoms included signs of raised intracranial pressure, seizures, and, in the case of spinal cord tumor, bladder dysfunction. In five cases, AGGs were localized supratentorially with three patients having multiple lobes involved. The tumors affected the frontal (n = 3 cases), parietal (n = 2), temporal (n = 2), and occipital lobes (n = 1), as well as the brainstem (n = 1) and the spinal cord (n = 2). Gross total tumor resection was achieved in six patients. The estimated 5-year overall survival rate +/- standard error was 88 +/- 12%, and the event-free survival rate was 63 +/- 17%. While gender and tumor location did not affect survival rates, gross total tumor resection provided a better overall survival than non-total resection.
conclusionThe prognosis of pediatric patients with AGG is good, especially for those who undergo gross total tumor resection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.