ArticleMolecular human reproduction2008
Genomic RNA profiling and the programme controlling preimplantation mammalian development.
Article in Molecular human reproduction, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Developmental Hurdles That Can Compromise Pregnancy during the First Month of Gestation in Cattle.Animals : an open access journal from MDPI · 2023Review
- Na+/K+ ATPase α1 and β3 subunits are localized to the basolateral membrane of trophectoderm cells in human blastocysts.Human reproduction (Oxford, England) · 2022Article
- Effects of palmitic acid on localization of embryo cell fate and blastocyst formation gene products.Reproduction (Cambridge, England) · 2022Article
- One-Step High-Throughput Telomerase Activity Measurement of Cell Populations, Single Cells, and Single-Enzyme Complexes.ACS omega · 2020Article
- Notch signaling in mouse blastocyst development and hatching.BMC developmental biology · 2020Article
- Adipokines Expression and Effects in Oocyte Maturation, Fertilization and Early Embryo Development: Lessons from Mammals and Birds.International journal of molecular sciences · 2020Review
- Selection of human blastocysts with a high implantation potential based on timely compaction.Journal of assisted reproduction and genetics · 2017Article
- The location of "8"-shaped hatching influences inner cell mass formation in mouse blastocysts.PloS one · 2017Article
- Exploring timing activation of functional pathway based on differential co-expression analysis in preimplantation embryogenesis.Oncotarget · 2016Article
- Observation of human embryonic behavior in vitro by high-resolution time-lapse cinematography.Reproductive medicine and biology · 2016Review
- MicroRNA expression and its association with DNA repair in preimplantation embryos.The Journal of reproduction and development · 2016Review
- Aquaporin7 plays a crucial role in tolerance to hyperosmotic stress and in the survival of oocytes during cryopreservation.Scientific reports · 2015Article
- Mammalian pre-implantation chromosomal instability: species comparison, evolutionary considerations, and pathological correlations.Systems biology in reproductive medicine · 2015Review
- Adaptive Transition of Aquaporin 5 Expression and Localization during Preimplantation Embryo Development by In Vitro Culture.Development & reproduction · 2014Article
- Analysis of compaction initiation in human embryos by using time-lapse cinematography.Journal of assisted reproduction and genetics · 2014Article
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- Detection and quantification of maternal-effect gene transcripts in mouse second polar bodies: potential markers of embryo developmental competence.Fertility and sterility · 2013Article
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- Human pre-implantation embryo development.Development (Cambridge, England) · 2012Review
- Research resource: interactome of human embryo implantation: identification of gene expression pathways, regulation, and integrated regulatory networks.Molecular endocrinology (Baltimore, Md.) · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preimplantation development shifts from a maternal to embryonic programme rapidly after fertilization. Although the majority of oogenetic products are lost during the maternal to embryonic transition (MET), several do survive this interval to contribute directly to supporting preimplantation development. Embryonic genome activation (EGA) is characterized by the transient expression of several genes that are necessary for MET, and while EGA represents the first major wave of gene expression, a second mid-preimplantation wave of transcription that supports development to the blastocyst stage has been discovered. The application of genomic approaches has greatly assisted in the discovery of stage specific gene expression patterns and the challenge now is to largely define gene function and regulation during preimplantation development. The basic mechanisms controlling compaction, lineage specification and blastocyst formation are defined. The requirement for embryo culture has revealed plasticity in the developmental programme that may exceed the adaptive capacity of the embryo and has fostered important research directions aimed at alleviating culture-induced changes in embryonic programming. New levels of regulation are emerging and greater insight into the roles played by RNA-binding proteins and miRNAs is required. All of this research is relevant due to the necessity to produce healthy preimplantation embryos for embryo transfer, to ensure that assisted reproductive technologies are applied in the most efficient and safest way possible.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.