Evidence map›Paper›PMID 19041590›Full record

ArticleAnnals of epidemiology2008

Risk factor effects and total mortality in older Japanese men in Japan and Hawaii.

Robert D Abbott, Hirotsugu Ueshima, Atsushi Hozawa, Tomonori Okamura, Takashi Kadowaki, Katsuyuki Miura, Nagako Okuda, Yasuyuki Nakamura, Akira Okayama, Yoshikuni Kita and 3 more

Abstract read
In one paragraph

Article in Annals of epidemiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Robert D AbbottDivision of Biostatistics and Epidemiology, University of Virginia School of Medicine, Charlottesville, VA 22908-0717, USA. rda3e@virginia.edu
Hirotsugu Ueshima
Atsushi Hozawa
Tomonori Okamura
Takashi Kadowaki
Katsuyuki Miura
Nagako Okuda
Yasuyuki Nakamura
Akira Okayama
Yoshikuni Kita
Beatriz L Rodriguez
Katsuhiko Yano
J David Curb
Shiga University of Medical Science · JPJapan Anti Tuberculosis Association · JPKuakini Medical Center · USKyoto Women's University · JPUniversity of Hawaiʻi at Mānoa · USUniversity of Virginia · US

Funding

EPIDEMIOLOGY OF AGING AND DEMENTIA - AUTOPSY RESEARCHR01AG017155 · NIA · KUAKINI MEDICAL CENTER · PI WHITE, LON RAY · 2000 to 2007
$6.7M
RISK FACTORS--PATHOLOGIC MARKERS FOR PARKINSON'S DISEASER01NS041265 · NINDS · PACIFIC HEALTH RESEARCH INSTITUTE · PI ROSS, GEORGE WEBSTER · 2000 to 2010
$5.8M
HONOLULU ASIA AGING STUDYN01AG042149 · NIA · KUAKINI MEDICAL CENTER · PI FOLEY, DANIEL · 1994 to 2000
$1.1M
HONOLULU HEART PROGRAMN01HC005102 · HC · KUAKINI MEDICAL CENTER · PI CURB, JESS DAVID · 1990 to 1997
–
NHLBI NIH HHS N01 HC005102NHLBI NIH HHS N01-HC-05102NIA NIH HHS 1-R01-AG17155-01A1NIA NIH HHS N01 AG042149NIA NIH HHS N01-AG-4-2149NIA NIH HHS R01 AG017155NINDS NIH HHS 1-R01-NS41265-01NINDS NIH HHS R01 NS041265
6 · The paper itself

Abstract

purposeWe sought to identify factors related to total mortality in older Japanese men in Japan and Hawaii.

methodsBaseline data were collected from 1980 to 1982 in 1379 men in Hawaii and 954 men in Japan. Ages ranged from 61 to 81 years, with mortality follow-up during a 19-year period.

resultsCompared with Japan, men in Hawaii had a 2-fold excess of diabetes and a 4-fold excess of prevalent coronary heart disease (P < .001). Total cholesterol and body mass index were also greater in Hawaiian men (P < .001). In contrast, men in Japan had greater systolic blood pressure and were nearly 3 times more likely to smoke cigarettes (P < .001). Although each cohort had elements of a poor risk factor profile, there was a 1.4-fold excess in the risk of death in Japan (49.4 vs. 36.2/1,000 person-years, P < .001). Although mortality was similar after risk factor adjustment, only blood pressure and cigarette smoking accounted for the higher risk of death in Japan.

conclusionsCigarette smoking and hypertension explain much of the excess mortality in Japan versus Hawaii. In this comparison of genetically similar cohorts, evidence further suggests that Japanese in Japan are equally susceptible to develop the same adverse risk factor conditions that exist in Hawaii.

Indexed as

AgedAged, 80 and overAlcohol DrinkingAsianBlood PressureCholesterolCoronary DiseaseDiabetes InsipidusHawaiiHumansHypertensionJapanLogistic ModelsMaleMiddle AgedMortalityCholesterol

Identifiers

PMID19041590
PMCPMC5576547
OpenAlexW2131580002

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.