Evidence map›Paper›PMID 19039700›Full record

ReviewJournal of neurovirology2009

The multiple sclerosis-associated retrovirus and its HERV-W endogenous family: a biological interface between virology, genetics, and immunology in human physiology and disease.

Antonina Dolei, Hervé Perron

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neurovirology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Trial
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  5. Article
  6. Article
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  8. Review
  9. Article
  10. Review
  11. HSV-1 and Endogenous Retroviruses as Risk Factors in Demyelination.International journal of molecular sciences · 2021
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. On the origin of a pathogenic HERV-W envelope protein present in multiple sclerosis lesions.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Antonina DoleiDepartment of Biomedical Sciences, Section of Microbiology, and Center of Excellence for Biotechnology Development and Biodiversity Research, University of Sassari, Viale San Pietro 43B, Sassari, Italy. doleivir@uniss.it
Hervé Perron

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This mini-review summarizes current knowledge of MSRV (multiple sclerosis-associated retrovirus), founder member of the type W family of human endogenous retroviruses (HERVs), its pathogenic potential and association with diseases. As retrotransposable elements, HERVs behave differently from stable genes, and cannot be studied with "Mendelian genetics" concepts only. They also display complex interactions with other HERV families, and with classical viruses. These concepts may contribute to unravelling the etiopathogenesis of complex diseases such as multiple sclerosis, schizophrenia, and other chronic multifactorial diseases.

Indexed as

AnimalsDiagnosis, DifferentialEndogenous RetrovirusesHumansMultiple SclerosisPrognosisSchizophreniaViral Envelope ProteinsViral Envelope Proteins

Identifiers

PMID19039700

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.