SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2009
Psychological insulin resistance: patient beliefs and implications for diabetes management.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
89 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Efficacy and safety among second-generation and other basal insulins in adult patients with type 1 diabetes: a systematic review and network meta-analysis.Naunyn-Schmiedeberg's archives of pharmacology · 2021Pooled it
- Psychological interventions to improve glycemic control in adults with type 2 diabetes: a systematic review and meta-analysis.BMJ open diabetes research & care · 2020Pooled it
- Addition of a single short-acting insulin bolus to basal insulin-supported oral therapy: a systematic review of data on the basal-plus regimen.BMJ open diabetes research & care · 2019Pooled it
- The association between insulin therapy and depression in patients with type 2 diabetes mellitus: a meta-analysis.BMJ open · 2018Pooled it
- Experiences and Perceived Influence of the Artificial Intelligence-Based Health Education Accurately Linking System (AI-HEALS) on Health Behaviors Among Patients With Type 2 Diabetes: Qualitative Study.Journal of medical Internet research · 2026Trial
- Effect of needle-free injection on psychological insulin resistance and insulin dosage in patients with type 2 diabetes.Frontiers in endocrinology · 2024Trial
- Noninferiority effects on glycemic control and β-cell function improvement in newly diagnosed type 2 diabetes patients: basal insulin monotherapy versus continuous subcutaneous insulin infusion treatment.Diabetes technology & therapeutics · 2012Trial
- Trial
- Initiating insulin as part of the Treating To Target in Type 2 Diabetes (4-T) trial: an interview study of patients' and health professionals' experiences.Diabetes care · 2010Trial
- Article
- Experienced stigma in Japanese outpatients with diabetes: Age and polypharmacy matter.Medicine · 2026Article
- Small Intestine-Targeted Long-Acting Oral Insulin Formulation Based on Engineered Milk Protein Nanoparticles.ACS applied bio materials · 2026Article
- Influencing factors of psychological insulin resistance among patients with type 2 diabetes: a systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2025Article
- Empagliflozin-based quadruple oral therapy for type 2 diabetes: a prospective cohort study.Scientific reports · 2025Article
- Prospects for the convergence of polyphenols with pharmaceutical drugs in type 2 diabetes: Challenges, risks, and strategies.Pharmacological reviews · 2025Review
- Factors Influencing Psychological Insulin Resistance Among Patients with Type 2 Diabetes in China: A Structural Equation Model Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Knowledge domain and emerging trends in medication literacy research from 2003 to 2024: a scientometric and bibliometric analysis using CiteSpace and VOSviewer.Frontiers in public health · 2025Article
- What Primary Care Clinicians Need to Know About Once-Weekly Insulins.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024Article
- Counseling for Insulin Icodec: A Proposed Practitioner's Guide.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024Article
- Once-weekly insulin icodec versus once-daily long-acting insulins for type 2 diabetes mellitus: Systematic review and meta-analysis.Metabolism open · 2024Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo define and understand patient psychological insulin resistance (PIR) and its impact on diabetes management.
methodsSystematic literature review of peer-refereed journals using the MEDLINE database, including all articles in English from 1985 to 2007. The population included patients with type 1 and type 2 diabetes, insulin naïve, and those currently using insulin. A total of 116 articles were reviewed.
resultsPIR is impacted by patients' beliefs and knowledge about diabetes and insulin, negative self-perceptions and attitudinal barriers, the fear of side effects and complications from insulin use, as well as lifestyle adaptations, restrictions required by insulin use, and social stigma. These etiological influences, both independently and in combination, constitute a patient's PIR and may result in the reluctance of patients to both initiate and intensify treatment, leading to delayed treatment initiation and compromised glucose control.
conclusionsPIR is complex and multifaceted. It plays an important, although often ignored, role in diabetes management. Assisting health care professionals in better understanding PIR from the patient's perspective should result in improved treatment outcomes. By tailoring treatments to patients' PIR, clinicians may be better able to help their patients begin insulin treatment sooner and improve compliance, thus facilitating target glycemic control.
Indexed as
Identifiers
19039679What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.