Evidence map›Paper›PMID 19037659›Full record

ArticleVirchows Archiv : an international journal of pathology2009

Mucinous adenocarcinoma of minor salivary glands: a high-grade malignancy prone to lymph node metastasis.

Fumio Ide, Kenji Mishima, Akio Tanaka, Ichiro Saito, Kaoru Kusama

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In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Salivary gland pathologies: evolution in classification and association with unique genetic alterations.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fumio IdeDepartment of Pathology, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, 230-8501, Japan. ide-f@tsurumi-u.ac.jp
Kenji Mishima
Akio Tanaka
Ichiro Saito
Kaoru Kusama
Tsurumi University · JPMeikai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salivary gland mucinous adenocarcinoma (MAC) is a rarely encountered and poorly understood tumor. We describe two additional cases presenting as a lip lesion of older women. The prognosis was dismal with one death and one patient with recurrent/metastatic disease. Combining these with 19 cases in the literature unveiled that intraoral MAC occurred primarily in the palate (43%) of elderly individuals (average 65 years) with slight male preponderance (59%). Tumor evolved slowly (>2 years) and most (60%) were diagnosed at an advanced stage. Local recurrences were common (33%) and cervical lymph node and distant metastases were frequent (63% and 29%, respectively). About half the patients (47%) died of tumor within 6 years. Both histologically and immunohistochemically, MAC lacked acinar, myoepithelial, and neuroendocrine phenotypes. Cytokeratins 7 and 20 and estrogen and progesterone receptors, in some combination, may assist to distinguish primary versus metastatic mucinous carcinoma. Minor salivary gland MAC belongs to a high-grade category with a significant risk of local recurrence, lymph node metastasis, and fatal outcome.

Indexed as

Adenocarcinoma, MucinousAgedAged, 80 and overFatal OutcomeFemaleHumansKeratin-20Keratin-7Lip NeoplasmsLymphatic MetastasisPrognosisReceptors, EstrogenRecurrenceSalivary Gland NeoplasmsKeratin-20Keratin-7Receptors, Estrogen

Identifiers

PMID19037659
OpenAlexW2019347842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.