Evidence map›Paper›PMID 19037639›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2009

Constant ambient temperature of 24 degrees C significantly reduces FDG uptake by brown adipose tissue in children scanned during the winter.

Katherine A Zukotynski, Frederic H Fahey, Stephen Laffin, Royal Davis, S Ted Treves, Frederick D Grant, Laura A Drubach

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 58 citations in OpenAlex.

  1. Trial
  2. Imaging insights of FDG-PET from neonates to infants.Japanese journal of radiology · 2025
    Review
  3. Brown fat activation demonstrated on FDG PET/CT predicts survival outcome.Journal of cancer research and clinical oncology · 2023
    Article
  4. Hot spot imaging in cardiovascular diseases: an information statement from SNMMI, ASNC, and EANM.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  5. Article
  6. Article
  7. Brown Adipose Tissue and Its Role in Insulin and Glucose Homeostasis.International journal of molecular sciences · 2021
    Review
  8. SNMMI Procedure Standard/EANM Practice Guideline on PediatricJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Article
  9. Article
  10. Guidelines on nuclear medicine imaging in neuroblastoma.European journal of nuclear medicine and molecular imaging · 2018
    Article
  11. Article
  12. Molecular imaging of brown adipose tissue in health and disease.European journal of nuclear medicine and molecular imaging · 2014
    Review
  13. Review
  14. Article
  15. Article
  16. A new connection between muscle and brown fat.The Journal of pediatrics · 2011
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Katherine A ZukotynskiDepartment of Radiology, Division of Nuclear Medicine/PET, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.
Frederic H Fahey
Stephen Laffin
Royal Davis
S Ted Treves
Frederick D Grant
Laura A Drubach
Boston Children's Hospital · USHarvard University · USBoston University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to determine if warming patients prior to and during (18)F-FDG uptake by controlling the room temperature could decrease uptake by brown adipose tissue (BAT).

methodsA group of 40 children underwent (18)F-FDG PET after being kept in the injection room at a constant temperature of 24 degrees C for half an hour before and 1 hour after intravenous tracer administration. The rate of uptake by BAT in this group was compared to the uptake in a control group of 45 patients who underwent PET when the injection room temperature was 21 degrees C.

resultsUptake by BAT occurred in 5% of studies in the temperature-controlled room compared to 31% of studies performed when the injection room temperature was 21 degrees C (p<0.002).

conclusionMaintaining room temperature at a constant 24 degrees C, half an hour prior to and during the period of FDG uptake significantly decreases accumulation of FDG in BAT in children.

Indexed as

Adipose Tissue, BrownCase-Control StudiesChildChild, PreschoolFalse Positive ReactionsFemaleFluorodeoxyglucose F18HumansInfantMalePositron-Emission TomographyRadiopharmaceuticalsRetrospective StudiesSeasonsTemperatureFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID19037639
OpenAlexW2026448404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.