Evidence map›Paper›PMID 19037221›Full record

ArticleObesity (Silver Spring, Md.)2008

Public health genomics: translating obesity genomics research into population health benefits.

Tanya Agurs-Collins, Muin J Khoury, Denise Simon-Morton, Deborah H Olster, Jennifer R Harris, John A Milner

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01443910 completednot on this mapstarted 2012, after this paper: background citation

Weight Management Interactions in a Virtual Clinical Environment

TypeobservationalSponsorNational Human Genome Research Institute (NHGRI)Ran2012 to 2016Enrolled318ConditionsHealthy Volunteers, Body Weight
NCT01888913 completednot on this mapstarted 2013, after this paper: background citation

Patient Perspectives and Simulated Clinical Interactions

TypeobservationalSponsorNational Human Genome Research Institute (NHGRI)Ran2013 to 2016Enrolled1,464ConditionsBody Weight
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Evaluating Approaches for Communication About Genomic Influences on Body Weight.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2015
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  7. Evaluating genomic tests from bench to bedside: a practical framework.BMC medical informatics and decision making · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Tanya Agurs-CollinsDivision of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. collinsta@mail.nih.gov
Muin J Khoury
Denise Simon-Morton
Deborah H Olster
Jennifer R Harris
John A Milner
National Institutes of Health · USNational Cancer Institute · USNational Heart Lung and Blood Institute · USOffice of Public Health Genomics · US

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

We examine how a public health genomics framework can be used to move genomic discoveries into clinical and public health practice for obesity prevention and treatment. There are four phases of translational research: T1: discovery to candidate health application; T2: health application to evidence-based practice guidelines; T3: practice guidelines to health practice; and T4: practice to population health impact. Types of multidisciplinary research and knowledge synthesis needed for each phase, as well as the importance of developing and disseminating evidence-based guidelines, are discussed. Because obesity genomics research is mostly in the discovery phase or in the very early phases of translation (T1), the authors present this framework to illustrate the range of translation activities needed to move genomic discoveries in obesity to actual applications that reduce the burden of obesity at the population level.

Indexed as

Genetic ResearchGenomicsBehavioral SciencesEnvironmentEvidence-Based MedicineGenetics, PopulationGenetic TestingHealth BehaviorHumansInformation DisseminationObesityPublic Health

Identifiers

PMID19037221
PMCPMC2736102
OpenAlexW2165592168

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.