ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2009
High bone mineral density is associated with high body mass index.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- The association between personal-social characteristics with bone mineral density in postmenopausal women with primary osteoporosis.Scientific reports · 2025Article
- Modified criteria for identifying elevated bone mass.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Risk of Osteoporosis Associated with Glucocorticoid Use in Pemphigus Vulgaris: Insights from a Retrospective Cohort Study.Dermatology practical & conceptual · 2025Article
- Cross-sectional study of patients with VCP multisystem proteinopathy 1 using dual-energy x-ray absorptiometry.Muscle & nerve · 2024Article
- Relationships among body weight, lipids and bone mass in elderly individuals with fractures: A case-control study.World journal of orthopedics · 2023Article
- The Impact of Age and Body Composition on Bone Density among Office Worker Women in Hungary.International journal of environmental research and public health · 2023Article
- Fat, adipokines, bone structure and bone regulatory factors associations in obesity.European journal of endocrinology · 2022Observational
- Metabolic syndrome is not associated to an increased risk of low bone mineral density in men at risk for osteoporosis.Journal of endocrinological investigation · 2022Article
- Article
- The French multicentre elevated bone mass study: prevalence and causes.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Article
- Adiposity and bone microarchitecture in the GLOW study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Article
- Bone Density and Body Fat Distribution in Postmenopausal Women.Materia socio-medica · 2021Article
- Adiposity reduces the risk of osteoporosis in Chinese rural population: the Henan rural cohort study.BMC public health · 2020Article
- The Genetic Architecture of High Bone Mass.Frontiers in endocrinology · 2020Review
- Differential effects of high fat diet and diet-induced obesity on skeletal acquisition in female C57BL/6J vs. FVB/NJ Mice.Bone reports · 2018Article
- Screening Gene Knockout Mice for Variation in Bone Mass: Analysis by μCT and Histomorphometry.Current osteoporosis reports · 2018Review
- Hand grip strength and maximum peak expiratory flow: determinants of bone mineral density of adolescent students.BMC pediatrics · 2018Article
- Racial and Ethnic Heterogeneity in the Association Between Total Cholesterol and Pediatric Obesity.International journal of environmental research and public health · 2015Article
- Association of Body Weight and Body Mass Index with Bone Mineral Density in Women and Men from Kosovo.Materia socio-medica · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summaryHigh BMD is an infrequent finding. In this retrospective cohort study of women 50 years and older, we documented a strong association between high BMD and high BMI.
introductionHigh bone mineral density (BMD) has been associated with genetic disorders and a variety of dietary, endocrine, metabolic, infectious and neoplastic diseases that in many cases warrant medical attention. Since body mass index (BMI) is closely correlated with BMD, we sought to explore the relationship between these two parameters in older women.
methodsWe conducted a retrospective clinical cohort study of 16,500 women 50 years and older who underwent baseline BMD testing between May 1998 and October 2002. Mean T-scores and Z-scores, and the proportions of women with high BMD (T-score +2.5 or greater, Z-score +2.0 or greater), were assessed according to BMI category.
resultsHigher BMI category was associated with higher mean T-scores and Z-scores at all sites (P < 0.001). The proportion of women with high BMD increased with each BMI category (P for trend <0.05). In women with a lumbar spine T-score of +2.5 or more, 43.5% were obese with BMI > 30 kg/m(2) (55.6% for the femoral neck and 73.1% for the total hip). For women with a lumbar spine Z-score of +2.0 or more, 37.2% were obese (42.0% for the femoral neck and 50.9% for the total hip). There was no evidence of a paradoxical increase in fracture rates in women with high BMD.
conclusionsHigh BMD is closely associated with elevated BMI in women. This should be taken into consideration prior to initiating extensive investigations for rare pathologies.
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