ArticleBritish journal of cancer2008
Body size in early life and risk of epithelial ovarian cancer: results from the Nurses' Health Studies.
Article in British journal of cancer, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Early-life body mass index and risks of breast, endometrial, and ovarian cancers: a dose-response meta-analysis of prospective studies.British journal of cancer · 2022Pooled it
- Obesity in children and adolescents and the risk of ovarian cancer: A systematic review and dose‒response meta-analysis.PloS one · 2022Pooled it
- Birth weight and adult cancer incidence: large prospective study and meta-analysis.Annals of oncology : official journal of the European Society for Medical Oncology · 2014Pooled it
- Associations of early life and adulthood adiposity with risk of epithelial ovarian cancer.Annals of oncology : official journal of the European Society for Medical Oncology · 2019Article
- Childhood Overweight, Tallness, and Growth Increase Risks of Ovarian Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019Article
- Birth weight and the risk of histological subtypes of ovarian and endometrial cancers: Results from the Copenhagen School Health Records Register.Gynecologic oncology · 2018Article
- Anthropometric characteristics and ovarian cancer risk and survival.Cancer causes & control : CCC · 2018Article
- Mendelian randomization study of adiposity-related traits and risk of breast, ovarian, prostate, lung and colorectal cancer.International journal of epidemiology · 2016Article
- Article
- Genetic variability in IGF-1 and IGFBP-3 and body size in early life.BMC public health · 2012Article
- Large body size and sedentary lifestyle during childhood and early adulthood and esophageal squamous cell carcinoma in a high-risk population.Annals of oncology : official journal of the European Society for Medical Oncology · 2012Article
- Occurrence and timing of childhood overweight and mortality: findings from the Third Harvard Growth Study.The Journal of pediatrics · 2012Article
- Body size in early life and adult levels of insulin-like growth factor 1 and insulin-like growth factor binding protein 3.American journal of epidemiology · 2011Article
- Article
- Body size and the risk of ovarian cancer by hormone therapy use in the California Teachers Study cohort.Cancer causes & control : CCC · 2010Article
- Anthropometric measures and risk of epithelial ovarian cancer: results from the nurses' health study.Obesity (Silver Spring, Md.) · 2010Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Adult body mass index (BMI) has been associated with ovarian cancer risk, but few studies have examined body size earlier in life. We prospectively examined associations of body fatness at ages 5 and 10, BMI at age 18, height, and birthweight with risk of epithelial ovarian cancer in the Nurses' Health Study (NHS: 110 311 women, 735 cases) and Nurses' Health Study II (NHSII: 113 059 women, 137 cases). Cox proportional hazards regression was used to estimate relative risks (RRs) and 95% confidence intervals (CIs). There was a weak inverse association between average body fatness at ages 5 and 10 and risk in the NHS (RR for heaviest vs most lean=0.81, 95% CI: 0.53-1.24, P for trend=0.04) and a nonsignificant positive association in the NHSII (RR=2.09, 95% CI: 0.98-4.48, P for trend=0.10), possibly due to differences in age and menopausal status. Height was positively associated with risk in both cohorts (RR for >or=1.75 vs <1.6 m=1.43, 95% CI: 1.05-1.96, P for trend=0.001). Body mass index at the age of 18 years and birthweight were not associated with risk. Further research should examine the biological mechanisms underlying the observed associations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.