ArticleJournal of experimental botany2009
Cotton metallothionein GhMT3a, a reactive oxygen species scavenger, increased tolerance against abiotic stress in transgenic tobacco and yeast.
Article in Journal of experimental botany, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 1 of them a synthesis that pooled it.
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Who cites it
83 citing papers in PubMed, 1 synthesis or guideline pooled it, 223 citations in OpenAlex.
- Plant responses to high temperature and drought: A bibliometrics analysis.Frontiers in plant science · 2022Pooled it
- Single-cell transcriptomic analyses reveal cellular and molecular patterns of rose petal responses to gray mold infection.Horticulture research · 2025Article
- Involvement of the Metallothionein gene OsMT2b in Drought and Cadmium Ions Stress in Rice.Rice (New York, N.Y.) · 2024Article
- Impact of salinity stress on cotton and opportunities for improvement through conventional and biotechnological approaches.BMC plant biology · 2024Review
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- Characterization of the Metallothionein Gene Family inAntioxidants (Basel, Switzerland) · 2023Article
- Article
- The putative vacuolar processing enzyme gene TaVPE3cB is a candidate gene for wheat stem pith-thickness.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Genome-wide analysis of the metallothionein gene family in cassava reveals its role in response to physiological stress through the regulation of reactive oxygen species.BMC plant biology · 2023Article
- Changes in physio-biochemical parameters and expression of metallothioneins in Avena sativa L. in response to drought.Scientific reports · 2023Article
- Examination of the Metallothionein Gene Family in Greater DuckweedPlants (Basel, Switzerland) · 2022Article
- Article
- Common and novel metabolic pathways related ESTs were upregulated in three date palm cultivars to ameliorate drought stress.Scientific reports · 2022Article
- Transcriptome and Metabolome Analysis of Upland Cotton (Life (Basel, Switzerland) · 2022Article
- Isolation and Characterization of thePlants (Basel, Switzerland) · 2022Article
- Metallothionein1A Regulates Rhizobial Infection and Nodulation inInternational journal of molecular sciences · 2022Article
- Genome-wide analysis of metallothionein gene family in maize to reveal its role in development and stress resistance to heavy metal.Biological research · 2022Article
- Mechanism of cotton resistance to abiotic stress, and recent research advances in the osmoregulation related genes.Frontiers in plant science · 2022Review
- An overview of salinity stress, mechanism of salinity tolerance and strategies for its management in cotton.Frontiers in plant science · 2022Review
- Role of Ectomycorrhizal Symbiosis Behind the Host Plants Ameliorated Tolerance Against Heavy Metal Stress.Frontiers in microbiology · 2022Review
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A cDNA clone encoding a 64-amino acid type 3 metallothionein protein, designated GhMT3a, was isolated from cotton (Gossypium hirsutum) by cDNA library screening. Northern blot analysis indicated that mRNA accumulation of GhMT3a was up-regulated not only by high salinity, drought, and low temperature stresses, but also by heavy metal ions, abscisic acid (ABA), ethylene, and reactive oxygen species (ROS) in cotton seedlings. Transgenic tobacco (Nicotiana tabacum) plants overexpressing GhMT3a showed increased tolerance against abiotic stresses compared with wild-type plants. Interestingly, the induced expression of GhMT3a by salt, drought, and low-temperature stresses could be inhibited in the presence of antioxidants. H(2)O(2) levels in transgenic tobacco plants were only half of that in wild-type (WT) plants under such stress conditions. According to in vitro assay, recombinant GhMT3a protein showed an ability to bind metal ions and scavenge ROS. Transgenic yeast overexpressing GhMT3a also showed higher tolerance against ROS stresses. Taken together, these results indicated that GhMT3a could function as an effective ROS scavenger and its expression could be regulated by abiotic stresses through ROS signalling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.