Evidence map›Paper›PMID 19031897›Full record

ArticleEnvironmental science & technology2008

Isolation and characterization of the gene associated with geosmin production in cyanobacteria.

Steven Giglio, Jiaoyang Jiang, Christopher P Saint, David E Cane, Paul T Monis

Open access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 124 citations in OpenAlex.

  1. Article
  2. The microbial biosynthesis of noncanonical terpenoids.Applied microbiology and biotechnology · 2024
    Review
  3. Review
  4. Review
  5. Construction and application of the genome-scale metabolic model ofFrontiers in bioengineering and biotechnology · 2023
    Article
  6. Article
  7. Cyanobacterial Genome Sequencing, Annotation, and Bioinformatics.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  8. Article
  9. Article
  10. Effects of elevated nitrogen on the growth and geosmin productivity of Dolichospermum smithii.Environmental science and pollution research international · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Steven GiglioAustralian Water Quality Centre, SA Water Corporation, Salisbury, SA 5108, Australia. steven.giglio@sawater.com.au
Jiaoyang Jiang
Christopher P Saint
David E Cane
Paul T Monis
Brown University · USSouth Australian Water Corporation · AUUniversity of Adelaide · AUUniversity of South Australia · AU

Funding

STEREOCHEMICAL STUDIES OF ISOPRENOID BIOSYNTHESISR01GM030301 · NIGMS · BROWN UNIVERSITY · PI CANE, DAVID E · 1985 to 2015
$5.4M
STEROCHEMICAL STUDIES 0F ISOPRENOID BIOSYNTHESISR37GM030301 · NIGMS · BROWN UNIVERSITY · PI CANE, DAVID E · 1994 to 2003
$1.8M
NIGMS NIH HHS GM30301NIGMS NIH HHS R01 GM030301NIGMS NIH HHS R37 GM030301
6 · The paper itself

Abstract

Geosmin is a secondary metabolite responsible for earthy tastes and odors in potable water supplies. Geosmin continues to be a challenge to water utility management regimes and remains one of the most common causes of consumer complaints, as the taste of "dirty" water may suggest a failed disinfection regime and that the water may be unsafe to drink. Although cyanobacteria have been reported to be largely responsible for these taste and odor events, the answer as to how or why geosmin is produced has eluded researchers. We describe here for the first time the mechanism by which geosmin is produced in a model cyanobacterium, Nostoc punctiforme PCC 73102 (ATCC 29133), which we demonstrate utilizes a single enzyme to catalyze the cyclization of farnesyl diphosphate to geosmin. Using this information, we have developed a PCR-based assay that allows the rapid detection of geosmin-producing cyanobacteria. This test may be utilized to confirm and track the emergence of taste and odor-producing cyanobacteria in any given water body and thus can be used as an early warning system by managers of water bodies that may suffer from adverse taste and odor episodes.

Indexed as

Genes, BacterialAmino Acid SequenceBacterial ProteinsCatalysisCyclizationDNA, BacterialEnvironmental MicrobiologyGas Chromatography-Mass SpectrometryMolecular Sequence DataNaphtholsNostocNucleic Acid DenaturationPolyisoprenyl PhosphatesPolymerase Chain ReactionSequence AlignmentSesquiterpenesBacterial ProteinsDNA, Bacterialfarnesyl pyrophosphategeosminNaphtholsPolyisoprenyl PhosphatesSesquiterpenes

Identifiers

PMID19031897
PMCPMC2746953
OpenAlexW2008665228

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.