Evidence map›Paper›PMID 19031448›Full record

ArticleJournal of medical virology2009

Development and implementation of a molecular diagnostic platform for daily rapid detection of 15 respiratory viruses.

Annika Tiveljung-Lindell, Maria Rotzén-Ostlund, Shawon Gupta, Richard Ullstrand, Lena Grillner, Benita Zweygberg-Wirgart, Tobias Allander

Open access · bronzeAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of medical virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 123 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Clinical analysis of Mycoplasma pneumoniae pneumonia combined with adenovirus infection in children with lobar pneumonia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
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  13. Article
  14. Interactions between seasonal human coronaviruses and implications for the SARS-CoV-2 pandemic: A retrospective study in Stockholm, Sweden, 2009-2020.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2021
    Article
  15. Laboratory detection methods for the human coronaviruses.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Review
  16. Article
  17. Genetic Sequence Variants inChildren (Basel, Switzerland) · 2020
    Article
  18. Article
  19. Observational
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Annika Tiveljung-LindellDepartment of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden. annika.tiveljung-lindell@karolinska.se
Maria Rotzén-Ostlund
Shawon Gupta
Richard Ullstrand
Lena Grillner
Benita Zweygberg-Wirgart
Tobias Allander
Karolinska University Hospital · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute respiratory tract infections are caused by a large number of viruses. Diagnostic methods have until recently been available only for a limited number of these viruses. With the objective to achieve sensitive assays for all respiratory viruses, a rational workflow in the laboratory, and a short turn-around time, a real-time PCR diagnostic platform for daily rapid detection of 15 respiratory viruses was developed. The system was evaluated on 585 stored nasopharyngeal aspirates from hospitalized children. Previous analysis by immunofluorescence and virus isolation identified viruses in 37% of the samples while the new PCR diagnostic panel detected 57% virus positive samples. The new platform was introduced in the laboratory in October 2007 and has then fully replaced the standard immunofluorescence assay for rapid detection of viruses and virus isolation.

Indexed as

AdolescentChildChild, PreschoolExudates and TransudatesFemaleHumansInfantInfant, NewbornMaleMolecular Diagnostic TechniquesNasopharynxPolymerase Chain ReactionRespiratory Tract InfectionsSensitivity and SpecificityVirus DiseasesViruses

Identifiers

PMID19031448
PMCPMC7167155
OpenAlexW1932471109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.