ReviewInternal and emergency medicine2009
Glucose dysmetabolism and prognosis in critical illness.
Review in Internal and emergency medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Energy, Protein, Carbohydrate, and Lipid Intakes and Their Effects on Morbidity and Mortality in Critically Ill Adult Patients: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2017Pooled it
- The association between triglyceride glucose-body mass index and mortality in intensive care unit patients: a propensity score matching analysis.European journal of medical research · 2025Article
- Metabolic Disturbances Associated with In-Hospital Complication and Mortality in Different Types of Pneumonia.Journal of clinical medicine · 2024Article
- Association between triglyceride glucose-body mass index and all-cause mortality in critically ill patients with acute myocardial infarction: retrospective analysis of the MIMIC-IV database.Frontiers in nutrition · 2024Article
- Association of hyperglycemia ratio and ventricular arrhythmia in critically ill patients admitted to the intensive care unit.BMC cardiovascular disorders · 2023Observational
- Prognostic factors in acute poisoning with central nervous system xenobiotics: development of a nomogram predicting risk of intensive care unit admission.Toxicology research · 2023Article
- Article
- Methanol poisoning as a new world challenge: A review.Annals of medicine and surgery (2012) · 2021Review
- Prognostic Factors of Outcome in Methanol Poisoning; an 8-year Retrospective Cross-sectional Study.Archives of academic emergency medicine · 2020Article
- Assessment of Blood Glucose and Electrolytes during Cardiopulmonary Bypass in Diabetic and Non-Diabetic Patients of Pakistan.Global journal of health science · 2016Article
- Incidence and predisposing factors for the development of disturbed glucose metabolism and DIabetes mellitus AFter Intensive Care admission: the DIAFIC study.Critical care (London, England) · 2015Observational
- Lymphocyte glucose and glutamine metabolism as targets of the anti-inflammatory and immunomodulatory effects of exercise.Mediators of inflammation · 2014Review
- Impact of repeated stress on traumatic brain injury-induced mitochondrial electron transport chain expression and behavioral responses in rats.Frontiers in neurology · 2013Article
- Hyperglycemia is a strong prognostic factor of lethality in methanol poisoning.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2011Article
- The prognostic role of gamma-glutamyltransferase activity in non-diabetic ST-elevation myocardial infarction.Internal and emergency medicine · 2011Article
- Glucose metabolism in cardiovascular surgery.HSR proceedings in intensive care & cardiovascular anesthesia · 2010Article
- Selenoprotein P regulation by the glucocorticoid receptor.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute hyperglycemia frequently present in stress conditions, has long been generally accepted as normal, and not thought to be a cause for concern since a moderate hyperglycemia in critically ill adult patients has been thought to be beneficial during the "fight or flight" response to ensure a supply of glucose as a source of energy to organs that do not require insulin for glucose uptake (i.e., the brain and the immune system). However, an increasing body of evidence associates the upon-admission degree and duration of hyperglycemia during critical illness with an adverse outcome. Hyperglycemia should be regarded as a part of the systemic and complex metabolic derangements observed in critical illness in response to stress and inflammation, which can lead, independent of initial disease, to multiorgan dysfunction and death. A tight glycemic control should be constantly pursued and achieved by insulin infusion bearing in mind that the therapeutic target is fighting the systemic inflammatory response and not merely the glucose plasma levels.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.