ArticleClinical research in cardiology : official journal of the German Cardiac Society2009
Efficacy of a 24-h primary percutaneous coronary intervention service on outcome in patients with ST elevation myocardial infarction in clinical practice.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Determinants of stroke following percutaneous coronary intervention in patients with acute coronary syndrome: a systematic review and meta-analysis.Annals of medicine · 2025Pooled it
- Drug-eluting stents in acute myocardial infarction: updated meta-analysis of randomized trials.Clinical research in cardiology : official journal of the German Cardiac Society · 2010Pooled it
- Copeptin, miRNA-208, and miRNA-499 as New Biomarkers for Early Detection of Acute Coronary Syndrome.Applied biochemistry and biotechnology · 2022Review
- Observational
- Management of patients with ST-segment elevation or non-ST-segment elevation acute coronary syndromes in cardiac rehabilitation centers.Clinical cardiology · 2014Article
- Short term cost effectiveness of a regional myocardial infarction network.Health economics review · 2013Article
- Influence of algorithm-based analgesia and sedation in patients after sudden cardiac arrest.Clinical research in cardiology : official journal of the German Cardiac Society · 2012Article
- Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction.Clinical research in cardiology : official journal of the German Cardiac Society · 2011Article
- Impact of minimising door-to-balloon times in ST-elevation myocardial infarction to less than 30 min on outcome: an analysis over an 8-year period in a tertiary care centre.Clinical research in cardiology : official journal of the German Cardiac Society · 2011Article
- Direct admission versus transfer of AMI patients for primary PCI.Clinical research in cardiology : official journal of the German Cardiac Society · 2011Article
- Primary angioplasty for any patient with ST-elevation myocardial infarction? Guideline-adherent feasibility and impact on mortality in a rural infarction network.Clinical research in cardiology : official journal of the German Cardiac Society · 2010Article
- Time of admission, quality of PCI care, and outcome of patients with ST-elevation myocardial infarction.Clinical research in cardiology : official journal of the German Cardiac Society · 2010Article
- Beneficial effect of delayed reperfusion in ST elevation myocardial infarction despite transmural necrosis documented in cardiac magnetic resonance imaging.Clinical research in cardiology : official journal of the German Cardiac Society · 2010Article
- Improved outcome in acute coronary syndrome by establishing a chest pain unit.Clinical research in cardiology : official journal of the German Cardiac Society · 2010Article
- Prognostic value of minimal blood flow restoration in patients with acute myocardial infarction after reperfusion therapy.Clinical research in cardiology : official journal of the German Cardiac Society · 2010Article
- Gender differences in patients with acute ST-elevation myocardial infarction complicated by cardiogenic shock.Clinical research in cardiology : official journal of the German Cardiac Society · 2009Article
- Contrast medium induced nephropathy in patients undergoing percutaneous coronary intervention for acute coronary syndrome: differences in STEMI and NSTEMI.Clinical research in cardiology : official journal of the German Cardiac Society · 2009Article
- In-hospital outcomes after elective and non-elective percutaneous coronary interventions in hospitals with and without on-site cardiac surgery backup.Clinical research in cardiology : official journal of the German Cardiac Society · 2009Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary percutaneous coronary intervention (PCI) for ST elevation myocardial infarction (STEMI) improves outcome in comparison to fibrinolysis. However, it is unclear whether patients treated in interventional facilities with 24-h primary PCI service have lower rates of adverse events.
methodsWe analyzed data of consecutive patients with STEMI prospectively enrolled in the German Acute Coronary Syndromes registry between July 2000 and November 2002 who were admitted to hospitals with catheterisation laboratory.
resultsOverall 6,350 patients were divided into two groups: 2,779 (43.8%) were treated in hospitals with and 3,571 (56.2%) without 24-h on-call cardiac catheter laboratories. 83.0% of the patients at facilities with and only 69.9% of the patients at facilities without 24-h PCI service received early reperfusion therapy (P < 0.001). Hospital death (7.4% vs. 9.9%, P < 0.001), non-fatal myocardial reinfarction (2.5% vs. 6.4%, P < 0.0001) and stroke (0.3 vs. 1.0%, P < 0.01) occurred significantly less often in patients treated in hospitals with 24-h primary PCI service. After adjustment for the confounding factors in the propensity score analysis the 24-h on-call strategy remained superior for the combined endpoint of death, reinfarction and stroke (OR 0.63, 95% CI 0.54-0.75).
conclusionsIn clinical practice the rate of patients receiving reperfusion therapy was significantly higher in hospitals with 24-h primary PCI service which was associated with an improved in-hospital outcome. Though the data was collected at a time that does not completely represent current clinical practice, these results could have an impact on planning efficient infarct networks in the future.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.