ArticleJournal of molecular evolution2008
Recoding of translation in turtle mitochondrial genomes: programmed frameshift mutations and evidence of a modified genetic code.
Article in Journal of molecular evolution, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 92 citations in OpenAlex.
- Mitogenomes reveal multiple evolutionary units and low genetic diversity of the critically endangered pancake tortoiseiScience · 2026Article
- Lineages to landscapes: mitogenomic insights and climate refugia informing proactive conservation of the endangered Tricarinate Hill Turtle (Melanochelys tricarinata) in the Indian subcontinent.Scientific reports · 2025Article
- Article
- Complete mitochondrial genome of the southern painted turtle (Mitochondrial DNA. Part B, Resources · 2024Article
- Complete mitochondrial genome of the razor-backed musk turtle (Mitochondrial DNA. Part B, Resources · 2023Article
- Mitochondrial Genomes in Perkinsus Decode Conserved Frameshifts in All Genes.Molecular biology and evolution · 2022Article
- Frameshift and wild-type proteins are often highly similar because the genetic code and genomes were optimized for frameshift tolerance.BMC genomics · 2022Article
- More discussion of minimalist species descriptions and clarifying some misconceptions contained in Meier et al. 2021.ZooKeys · 2022Article
- Complete mitochondrial genome of the Cumberland slider (Mitochondrial DNA. Part B, Resources · 2021Article
- Characterization of the complete mitogenomes of Baillon's CrakeMitochondrial DNA. Part B, Resources · 2021Article
- Multiple origins of a frameshift insertion in a mitochondrial gene in birds and turtles.GigaScience · 2021Article
- The complete mitochondrial genome of Indian CuckooMitochondrial DNA. Part B, Resources · 2021Article
- The mitogenome of common snipe,Mitochondrial DNA. Part B, Resources · 2021Article
- Prediction of mitochondrial genome-wide variation through sequencing of mitochondrion-enriched extracts.Scientific reports · 2020Article
- The role of selection in the evolution of marine turtles mitogenomes.Scientific reports · 2020Article
- Structural Variation of the Turtle Mitochondrial Control Region.Journal of molecular evolution · 2020Article
- Unorthodox features in two venerid bivalves with doubly uniparental inheritance of mitochondria.Scientific reports · 2020Article
- The Complete Mitochondrial Genome ofGenes · 2019Article
- Chimeric Translation for Mitochondrial Peptides: Regular and Expanded Codons.Computational and structural biotechnology journal · 2019Article
- The first complete mitogenome of Indian star tortoise (Mitochondrial DNA. Part B, Resources · 2018Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A +1 frameshift insertion has been documented in the mitochondrial gene nad3 in some birds and reptiles. By sequencing polyadenylated mRNA of the chicken (Gallus gallus), we have shown that the extra nucleotide is transcribed and is present in mature mRNA. Evidence from other animal mitochondrial genomes has led us to hypothesize that certain mitochondrial translation systems have the ability to tolerate frameshift insertions using programmed translational frameshifting. To investigate this, we sequenced the mitochondrial genome of the red-eared slider turtle (Trachemys scripta), where both the widespread nad3 frameshift insertion and a novel site in nad4l were found. Sequencing the region surrounding the insertion in nad3 in a number of other turtles and tortoises reveal general mitochondrial +1 programmed frameshift site features as well as the apparent redefinition of a stop codon in Parker's snake-neck turtle (Chelodina parkeri), the first known example of this in vertebrate mitochondria.
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