ArticleApplied and environmental microbiology2009
Regulatory and DNA repair genes contribute to the desiccation resistance of Sinorhizobium meliloti Rm1021.
Article in Applied and environmental microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 45 citations in OpenAlex.
- Biogeographic and Genomic Signatures of Thermal Adaptation in Facultative Symbionts.Microbial ecology · 2025Article
- GacA reduces virulence and increases competitiveness in planta in the tumorigenic olive pathogenFrontiers in plant science · 2024Article
- Metabolic versatility of soil microbial communities below the rocks of the hyperarid Dalangtan Playa.Applied and environmental microbiology · 2023Article
- Effects of rehydration on physiological and transcriptional responses of a water-stressed rhizobium.Journal of microbiology (Seoul, Korea) · 2022Article
- A Tn-seq Screen of Streptococcus pneumoniae Uncovers DNA Repair as the Major Pathway for Desiccation Tolerance and Transmission.Infection and immunity · 2021Article
- Desiccation-induced cell damage in bacteria and the relevance for inoculant production.Applied microbiology and biotechnology · 2020Review
- Identification of Novel Genes Mediating Survival ofFrontiers in microbiology · 2020Article
- Over-Expression of UV-Damage DNA Repair Genes and Ribonucleic Acid Persistence Contribute to the Resilience of Dried Biofilms of the Desert CyanobacetriumFrontiers in microbiology · 2019Article
- MostmSphere · 2018Article
- A network of regulators promotes dehydration tolerance in Escherichia coli.Environmental microbiology · 2018Article
- Salt resistance genes revealed by functional metagenomics from brines and moderate-salinity rhizosphere within a hypersaline environment.Frontiers in microbiology · 2015Article
- A putative bifunctional histidine kinase/phosphatase of the HWE family exerts positive and negative control on the Sinorhizobium meliloti general stress response.Journal of bacteriology · 2014Article
- Towards decrypting cryptobiosis--analyzing anhydrobiosis in the tardigrade Milnesium tardigradum using transcriptome sequencing.PloS one · 2014Article
- Identification and characterization of a NaCl-responsive genetic locus involved in survival during desiccation in Sinorhizobium meliloti.Applied and environmental microbiology · 2013Article
- Desiccation induces viable but Non-Culturable cells in Sinorhizobium meliloti 1021.AMB Express · 2012Article
- Sinorhizobium meliloti sigma factors RpoE1 and RpoE4 are activated in stationary phase in response to sulfite.PloS one · 2012Article
- Biosynthesis of compatible solutes in rhizobial strains isolated from Phaseolus vulgaris nodules in Tunisian fields.BMC microbiology · 2010Article
- A new small regulatory protein, HmuP, modulates haemin acquisition in Sinorhizobium meliloti.Microbiology (Reading, England) · 2010Article
- Dual control of Sinorhizobium meliloti RpoE2 sigma factor activity by two PhyR-type two-component response regulators.Journal of bacteriology · 2010Article
- Identification of a novel ABC transporter required for desiccation tolerance, and biofilm formation in Rhizobium leguminosarum bv. viciae 3841.FEMS microbiology ecology · 2010Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sinorhizobium meliloti can form a nitrogen-fixing symbiotic relationship with alfalfa after bacteria in the soil infect emerging root hairs of the growing plant. To be successful at this, the bacteria must be able to survive in the soil between periods of active plant growth, including when conditions are dry. The ability of S. meliloti to withstand desiccation has been known for years, but genes that contribute to this phenotype have not been identified. Transposon mutagenesis was used in combination with novel screening techniques to identify four desiccation-sensitive mutants of S. meliloti Rm1021. DNA sequencing of the transposon insertion sites identified three genes with regulatory functions (relA, rpoE2, and hpr) and a DNA repair gene (uvrC). Various phenotypes of the mutants were determined, including their behavior on several indicator media and in symbiosis. All of the mutants formed an effective symbiosis with alfalfa. To test the hypothesis that UvrC-related excision repair was important in desiccation resistance, uvrA, uvrB, and uvrC deletion mutants were also constructed. These strains were sensitive to DNA damage induced by UV light and 4-NQO and were also desiccation sensitive. These data indicate that uvr gene-mediated DNA repair and the regulation of stress-induced pathways are important for desiccation resistance.
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