ArticleTransplantation reviews (Orlando, Fla.)2009
Mixed chimerism to induce tolerance: lessons learned from nonhuman primates.
Article in Transplantation reviews (Orlando, Fla.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Successful Induction of Specific Immunological Tolerance by Combined Kidney and Hematopoietic Stem Cell Transplantation in HLA-Identical Siblings.Frontiers in immunology · 2022Trial
- Unlocking Transplant Tolerance with Biomaterials.Advanced healthcare materials · 2025Review
- The hematopoietic system in the context of regenerative medicine.Methods (San Diego, Calif.) · 2016Review
- Tolerance of Lung Allografts Achieved in Nonhuman Primates via Mixed Hematopoietic Chimerism.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2015Article
- Mesenchymal Stem Cells and Co-stimulation Blockade Enhance Bone Marrow Engraftment and Induce Immunological Tolerance.International journal of organ transplantation medicine · 2015Article
- Chimerism-based experimental models for tolerance induction in vascularized composite allografts: Cleveland clinic research experience.Clinical & developmental immunology · 2013Article
- Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primates.Science translational medicine · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The mixed chimerism approach has been demonstrated to be an effective means of inducing allograft tolerance. Based on our rodent studies on mixed chimerism, we previously developed a clinically relevant nonmyeloablative preparative regimen that permits the induction of mixed chimerism and renal allograft tolerance following donor bone marrow transplantation in major histocompatibility complex fully mismatched cynomolgus monkeys. This approach has been successfully extended to HLA matched or mismatched kidney transplant recipients. In the manuscript, we summarize some of the important conclusions made in our laboratories regarding induction of mixed chimerism and allograft tolerance in a nonhuman primate model.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.