ReviewCytokine & growth factor reviews
p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiation.
Review in Cytokine & growth factor reviews. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 43 citations in OpenAlex.
- USP24-dependent STAT2 stabilization mediates physiologic and pathologic bone formation.Cell death & disease · 2026Article
- Interferon-induced protein 16 expression in colorectal cancer and its correlation with proliferation and immune signature markers.Oncology letters · 2021Article
- Activation and Immune Regulation Mechanisms of PYHIN Family During Microbial Infection.Frontiers in microbiology · 2021Review
- P200 family protein IFI204 negatively regulates type I interferon responses by targeting IRF7 in nucleus.PLoS pathogens · 2019Article
- Structural analysis of the HIN1 domain of interferon-inducible protein 204.Acta crystallographica. Section F, Structural biology communications · 2019Article
- Ifi204/p204, a new piece in the sepsis puzzle.Annals of translational medicine · 2018Article
- RNA-Seq analysis of interferon inducible p204-mediated network in anti-tumor immunity.Scientific reports · 2018Article
- p204 Is Required for Canonical Lipopolysaccharide-induced TLR4 Signaling in Mice.EBioMedicine · 2018Article
- The Telomeric Response to Viral Infection.Viruses · 2017Review
- Transcriptomic analysis of purified human cortical microglia reveals age-associated changes.Nature neuroscience · 2017Article
- Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages.The Journal of clinical investigation · 2017Article
- Gene expression patterns in transgenic mouse models of hypertrophic cardiomyopathy caused by mutations in myosin regulatory light chain.Archives of biochemistry and biophysics · 2016Article
- The roles of interferon-inducible p200 family members IFI16 and p204 in innate immune responses, cell differentiation and proliferation.Genes & diseases · 2015Article
- Wanderings in biochemistry.The Journal of biological chemistry · 2014Article
- Interferons as inducers of apoptosis in malignant cells.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2013Review
- The mammalian PYHIN gene family: phylogeny, evolution and expression.BMC evolutionary biology · 2012Article
- Emerging roles for the interferon-inducible p200-family proteins in sex bias in systemic lupus erythematosus.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2011Review
- IFI16 is an innate immune sensor for intracellular DNA.Nature immunology · 2010Article
- The p200 family protein p204 as a modulator of cell proliferation and differentiation: a brief survey.Cellular and molecular life sciences : CMLS · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The interferon-inducible p200 family comprises a group of homologous mouse and human proteins. Most of these have an N-terminal DAPIN domain and one or two partially conserved, 200 amino acid long C-terminal domains (designated as 200X domain). These proteins play important roles in the regulation of cell proliferation, tissue differentiation, apoptosis and senescence. p200 family proteins are involved also in autoimmunity and the control of tumor growth. These proteins function by binding to various target proteins (e.g. transcription factors, signaling proteins, oncoproteins and tumor suppressor proteins) and modulating target activity. This review concentrates on p204, a murine member of the family and its roles in regulating cell proliferation, cell and tissue differentiation (e.g. of skeletal muscle myotubes, beating cardiac myocytes, osteoblasts, chondrocytes and macrophages) and signaling by Ras proteins. The expression of p204 in various tissues as promoted by tissue-specific transcription factors, its distribution among subcellular compartments, and the controls of these features are also discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.