Evidence map›Paper›PMID 19026936›Full record

ReviewEndocrinology and metabolism clinics of North America2008

The microbes of the intestine: an introduction to their metabolic and signaling capabilities.

William W L Hsiao, Christine Metz, Davinder P Singh, Jesse Roth

Open access · greenAbstract readReview
In one paragraph

Review in Endocrinology and metabolism clinics of North America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Roles of the gut microbiome in weight management.Nature reviews. Microbiology · 2023
    Pooled it
  2. Article
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  6. Review
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  15. Article
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  17. Microbiota Targeted Interventions of ProbioticAntioxidants (Basel, Switzerland) · 2021
    Review
  18. Review
  19. Microbial Ecosystem in Diabetes Mellitus: Consideration of the Gastrointestinal System.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

William W L HsiaoInstitute for Genome Sciences, University of Maryland, School of Medicine, 20 Penn Street, Baltimore, MD 21201, USA.
Christine Metz
Davinder P Singh
Jesse Roth
Feinstein Institute for Medical Research · USUniversity of Maryland, Baltimore · US

Funding

Trace the flow of genes in the gut microbiome of obese and lean twin pairsP01DK078669 · NIDDK · WASHINGTON UNIVERSITY · PI GORDON, JEFFREY I · 2007 to 2018
$16.0M
NIDDK NIH HHS 1P01 DK 78669NIDDK NIH HHS P01 DK078669
6 · The paper itself

Abstract

This article summarizes advances in the field of host-microbe interactions in the gut. The human gut is home to a complex community of microbes (the microbiota) that plays a critical role in host nutrient acquisition and metabolism, development of intestinal epithelial cells, and host immune system. Genetic background, nutritional status, and environmental factors influence the structure and function of the gut microbiota. Networks for cell-cell communication include microbes actively communicating with microbes of the same and other species; host cells recognizing and interacting with commensal versus pathogenic organisms; and microbes releasing peptides that resemble peptide hormones of vertebrates, possibly influencing host cell function.

Indexed as

AnimalsHumansImmunity, InnateIntestinal MucosaIntestinesMetabolismMetagenomeMicrobiological PhenomenaModels, BiologicalQuorum SensingSignal TransductionSymbiosis

Identifiers

PMID19026936
PMCPMC4411945
OpenAlexW1982644410

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.