Evidence map›Paper›PMID 19026340›Full record

ReviewClinics in perinatology2008

The diagnosis, management, and postnatal prevention of intraventricular hemorrhage in the preterm neonate.

Heather J McCrea, Laura R Ment

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in perinatology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 4 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 4 syntheses or guidelines pooled it, 272 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Intraventricular hemorrhage and posthemorrhagic hydrocephalus in preterm infants: diagnosis, classification, and treatment options.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Pooled it
  5. Trial
  6. A FAR-Out approach for evaluating the impact of clinical practice changes on severe intracranial hemorrhage in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2026
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Heather J McCreaYale University School of Medicine, New Haven, CT 06510, USA.
Laura R Ment
Yale University · US

Funding

RANDOMIZED INDOMETHACIN GMH/IVH PREVENTION TRIALR01NS027116 · NINDS · YALE UNIVERSITY · PI MENT, LAURA R. · 1989 to 2009
$11.9M
Gene Targets for Intraventricular Hemorrhage (IVH)R01NS053865 · NINDS · YALE UNIVERSITY · PI MENT, LAURA R. · 2007 to 2011
$7.9M
NINDS NIH HHS NS 27116NINDS NIH HHS NS 53865NINDS NIH HHS R01 NS027116NINDS NIH HHS R01 NS053865
6 · The paper itself

Abstract

Intraventricular hemorrhage (IVH) occurs in 20% to 25% of very low birthweight preterm neonates and may be associated with significant sequelae. Infants who have IVH are at risk for posthemorrhagic hydrocephalus and periventricular leukomalacia; as many as 75% of those who have parenchymal involvement of hemorrhage suffer significant neurodevelopmental disability. Because of the prevalence of IVH and the medical and societal impact of this disease, many postnatal pharmacologic prevention strategies have been explored. Randomized clinical prevention trials should provide long-term neurodevelopmental follow-up to assess the impact of preterm birth, injury, and pharmacologic intervention on the developing brain.

Indexed as

Infant, PrematureCerebral HemorrhageCerebral VentriclesCoagulantsCyclooxygenase InhibitorsFactor VIIaHumansIbuprofenIndomethacinInfant, NewbornPhenobarbitalCoagulantsCyclooxygenase InhibitorsFactor VIIaIbuprofenIndomethacinPhenobarbital

Identifiers

PMID19026340
PMCPMC2901530
OpenAlexW2104335628

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.