Evidence map›Paper›PMID 19025788›Full record

ReviewGenetic epidemiology2009

Ecogeographic genetic epidemiology.

Chantel D Sloan, Eric J Duell, Xun Shi, Rebecca Irwin, Angeline S Andrew, Scott M Williams, Jason H Moore

Abstract readReview
In one paragraph

Review in Genetic epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Genetics: A New Landscape for Medical Geography.Annals of the Association of American Geographers. Association of American Geographers · 2013
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chantel D SloanComputational Genetics Laboratory, Department of Genetics, Dartmouth Medical School, Lebanon, New Hampshire, USA.
Eric J Duell
Xun Shi
Rebecca Irwin
Angeline S Andrew
Scott M Williams
Jason H Moore

Funding

THE ROLE OF CAL IN CIF-MEDIATED DEGRADATION OF CFTRP20RR018787 · NCRR · DARTMOUTH COLLEGE · PI O'TOOLE, GEORGE A. · 2003 to 2011
$21.9M
Bioinformatics Strategies: Biodefense Vaccine ResearchR01AI059694 · NIAID · DARTMOUTH COLLEGE · PI MOORE, JASON H. · 2004 to 2012
$4.5M
Machine Learning Prediction of Cancer SusceptibilityR01LM009012 · NLM · UNIVERSITY OF PENNSYLVANIA · PI MOORE, JASON H. · 2006 to 2014
$3.3M
NCRR NIH HHS P20 RR018787NCRR NIH HHS RR018787NIAID NIH HHS AI59694NIAID NIH HHS R01 AI059694NLM NIH HHS LM009012NLM NIH HHS R01 LM009012
6 · The paper itself

Abstract

Complex diseases such as cancer and heart disease result from interactions between an individual's genetics and environment, i.e. their human ecology. Rates of complex diseases have consistently demonstrated geographic patterns of incidence, or spatial "clusters" of increased incidence relative to the general population. Likewise, genetic subpopulations and environmental influences are not evenly distributed across space. Merging appropriate methods from genetic epidemiology, ecology and geography will provide a more complete understanding of the spatial interactions between genetics and environment that result in spatial patterning of disease rates. Geographic information systems (GIS), which are tools designed specifically for dealing with geographic data and performing spatial analyses to determine their relationship, are key to this kind of data integration. Here the authors introduce a new interdisciplinary paradigm, ecogeographic genetic epidemiology, which uses GIS and spatial statistical analyses to layer genetic subpopulation and environmental data with disease rates and thereby discern the complex gene-environment interactions which result in spatial patterns of incidence.

Indexed as

Epidemiologic MethodsGenetics, PopulationEcosystemEnvironmentGenetics, MedicalGeographyHumansSoftware

Identifiers

PMID19025788
PMCPMC2672969

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.