ArticleAIDS patient care and STDs2008
Health-related quality of life in HIV-infected patients: the role of substance use.
Article in AIDS patient care and STDs, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07414459 (Combining Social Network Strategies and Routine Substance Use Screening), which is not on this map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Combining Social Network Strategies and Routine Substance Use Screening
Who cites it
60 citing papers in PubMed, 116 citations in OpenAlex.
- Limited Impact of Cannabidiol on Health-related Quality of Life of People With Long-term Controlled HIV: A Double-blind, Randomized, Controlled Trial.Open forum infectious diseases · 2024Trial
- Factors That Affect Quality of Life among People Living with HIV Attending an Urban Clinic in Uganda: A Cohort Study.PloS one · 2015Trial
- Peer support and improved quality of life among persons living with HIV on antiretroviral treatment: a randomised controlled trial from north-eastern Vietnam.Health and quality of life outcomes · 2012Trial
- Multiple substance use by HIV status among United States adults, 2021-2024.Addictive behaviors reports · 2026Article
- Health-Related Quality of Life in Well-treated People With HIV and Comparators Over an 8-year Period: A Longitudinal Analysis From the Prospective AGEhIV Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- COVID-19 and the Syndemic of Intimate Partner Violence, Mental Health, Substance Use, and HIV Care Engagement Among Black Sexual Minority Men Living with HIV in the US South.International journal of environmental research and public health · 2025Article
- Characteristics linked to mortality risk among individuals with drug use disorders enrolled in drug rehabilitation facilities in Japan.PCN reports : psychiatry and clinical neurosciences · 2025Article
- Correlates of Using Medically-Authorized Cannabis in a Large Cohort of People Living with HIV Who Use Cannabis.AIDS and behavior · 2025Article
- Quality of Life in People With HIV at the End of Life: Preliminary Results From the Last Gift Observational Cohort Study.Journal of acquired immune deficiency syndromes (1999) · 2025Observational
- Article
- Patterns of Health-related Quality of Life in Men Who Inject Drugs: A Survey in Southeast Iran.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024Article
- Pulmonary Function and Quality of Life in Aging Men With and Without HIV from the Multicenter AIDS Cohort Study.AIDS research and human retroviruses · 2023Article
- The temporal relationship of alcohol use and subsequent self-reported health status among people with HIV.American journal of medicine open · 2023Article
- Disentangling Medicinal and Recreational cannabis Use Among People Living with HIV: An Ecological Momentary Assessment Study.AIDS and behavior · 2023Article
- Article
- Polysubstance Use Patterns Associated With HIV Disease Severity Among Those With Substance Use Disorders: A Latent Class Analysis.Journal of studies on alcohol and drugs · 2023Article
- The relationship of alcohol and other drug use during the COVID-19 pandemic among people with or at risk of HIV; A cross-sectional survey of people enrolled in Collaborating Consortium of Cohorts Producing NIDA Opportunities (C3PNO) cohorts.Drug and alcohol dependence · 2022Article
- Prevalence of depression and associated factors among people living with HIV/AIDS in public hospitals of Southeast Ethiopia.BMC psychiatry · 2022Article
- Gender Differences in Depression and Quality of Life in Current and Abstinent Ketamine Users.International journal of environmental research and public health · 2021Article
- African American/Black and Latino Adults with Detectable HIV Viral Load Evidence Substantial Risk for Polysubstance Substance Use and Co-occurring Problems: A Latent Class Analysis.AIDS and behavior · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
HIV infection and substance use disorders are chronic diseases with complex contributions to health-related quality of life (HRQOL). We conducted a cross-sectional survey of 951 HIV-infected adults receiving care at 14 HIV Research Network sites in 2003 to estimate associations between HRQOL and specific substance use among HIV-infected patients. HRQOL was assessed by multi-item measures of physical and role functioning, general health, pain, energy, positive affect, anxiety, and depression. Mental and physical summary scales were developed by factor analysis. We used linear regression to estimate adjusted associations between HRQOL and current illicit use of marijuana, analgesics, heroin, amphetamines, cocaine, sedatives, inhalants, hazardous/binge alcohol, and drug use severity. Current illicit drug use was reported by 37% of subjects. Mental HRQOL was reduced for current users [adjusted beta coefficient -9.66, 95% confidence interval [(CI]) -13.4, -5.94] but not former users compared with never users. Amphetamines and sedatives were associated with large decreases in mental (amphetamines: beta = -22.8 [95% CI -33.5, -12.0], sedatives: beta = -18.6 [95% CI -26.2, -11.0]), and physical HRQOL (amphetamines: beta = -11.5 [95% CI -22.6, -0.43], sedatives: beta = -13.2 [95% CI -21.0, -5.36]). All illicit drugs were associated with decreased mental HRQOL: marijuana (beta = -7.72 [95% CI -12.0, -3.48]), non-prescription analgesics (beta = -13.4 [95% CI -20.8, -6.07]), cocaine (beta = -10.5 [95% CI -16.4, -4.67]), and inhalants (beta = -14.0 [95% CI -24.1, -3.83]). Facilitating sobriety for patients with attention to specific illicit drugs represents an important avenue for elevating HRQOL in patients living with HIV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.