Evidence map›Paper›PMID 19023831›Full record

Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2008

Risk factors for treatment failure in smokers: relationship to alcohol use and to lifetime history of an alcohol use disorder.

Robert F Leeman, Sherry A McKee, Benjamin A Toll, Suchitra Krishnan-Sarin, Judith L Cooney, Robert W Makuch, Stephanie S O'Malley

Erratum issued Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05430529 (Development and a Pilot Randomized Controlled Trial of a Brief Alcohol Intervention During Smoking Cessation Treatment Delivered by Healthcare Professionals), which is not on this map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05430529 nacompletednot on this mapstarted 2022, after this paper: background citation

Development and a Pilot Randomized Controlled Trial of a Brief Alcohol Intervention During Smoking Cessation Treatment Delivered by Healthcare Professionals

TypeinterventionalSponsorThe University of Hong KongRan2022 to 2022Enrolled100ConditionsSmoking CessationArmsStandard Smoke Cessation Service, Short Advice for Control Group, Brief Alcohol Intervention for Intervention Group
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2014
    Pooled it
  3. Trial
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  11. Individual and combined effects of multiple high-risk triggers on postcessation smoking urge and lapse.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2014
    Trial
  12. Trial
  13. Expectancies regarding the interaction between smoking and substance use in alcohol-dependent smokers in early recovery.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2012
    Trial
  14. Trial
  15. Trial
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  17. Alcohol use and initial smoking lapses among heavy drinkers in smoking cessation treatment.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2010
    Trial
  18. Trial
  19. Article
  20. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2023
    Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

7 authors.

Robert F LeemanDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA. robert.leeman@yale.edu
Sherry A McKee
Benjamin A Toll
Suchitra Krishnan-Sarin
Judith L Cooney
Robert W Makuch
Stephanie S O'Malley

Funding

SUBSTANCE ABUSEK12DA000167 · NIDA · YALE UNIVERSITY · PI STEPHANIE S O'MALLEY, Marc N Potenza · 1991 to 2026
$17.7M
Tobacco Dependence &Risk Factors for Treatment FailureP50AA015632 · NIAAA · YALE UNIVERSITY · PI MAKUCH, ROBERT W. · 2004 to 2008
$9.2M
TOBACCO DEPENDENCE AND RISK FACTORS FOR TREATMENT FAILURP50DA013334 · NIDA · YALE UNIVERSITY · PI O'MALLEY, STEPHANIE S · 1999 to 2003
$8.0M
Research Training Fellowship in Substance use and Addiction (RTFSA)T32DA007238 · NIDA · YALE UNIVERSITY · PI BRIAN D. KILUK, ISMENE L. PETRAKIS · 1988 to 2026
$5.7M
Improving Alcoholism TreatmentK05AA014715 · NIAAA · YALE UNIVERSITY · PI O'MALLEY, STEPHANIE S · 2004 to 2013
$2.1M
NIAAA NIH HHS AA014715NIAAA NIH HHS AA015632NIAAA NIH HHS K05 AA014715NIAAA NIH HHS P50 AA015632NIDA NIH HHS DA000167NIDA NIH HHS DA07238NIDA NIH HHS DA13334NIDA NIH HHS K12 DA000167NIDA NIH HHS P50 DA013334NIDA NIH HHS T32 DA007238
6 · The paper itself

Abstract

Little is known about the impact of alcohol involvement on smoking cessation relapse or possible mechanisms for these associations. We addressed these issues using data from a randomized clinical trial of two types of framed messages (gain vs. loss) in conjunction with open label sustained-release (SR) bupropion (Toll et al., 2007) (N = 249). Participants were categorized according to whether or not they were diagnosed with a lifetime alcohol use disorder (AUD; i.e., current or past alcohol abuse or past alcohol dependence) and according to three levels of alcohol use: abstinence, moderate, or hazardous use. Alcohol use categories were established for drinking at baseline, during the 6-week treatment period and through 12 weeks post-quit. There were few significant differences by baseline alcohol use level or AUD history for a series of predictors of smoking cessation failure (e.g., depressive symptoms). During treatment and follow-up, the probability of any smoking on heavy drinking days was significantly higher than the probability of smoking on moderate drinking or abstinent days. AUD history did not predict smoking cessation relapse in any analysis, nor were any alcohol usexAUD history interactions significant. Moderate alcohol users and, to a lesser extent, abstainers from alcohol at baseline were less likely than hazardous drinkers to have relapsed at 12 weeks post-quit. Based on these findings, it appears that risk of any smoking and of relapse was associated primarily with heavy drinking days and a hazardous pattern of use respectively, rather than with moderate drinking.

Indexed as

Severity of Illness IndexSmoking PreventionAdultAgedAlcohol DrinkingAlcoholismComorbidityFemaleHumansMaleMiddle AgedMotivationRandomized Controlled Trials as TopicRecurrenceRisk FactorsSmoking

Identifiers

PMID19023831
PMCPMC2764010

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.