Evidence map›Paper›PMID 19023667›Full record

ArticleEnvironmental geochemistry and health2009

Towards the development of a multidisciplinary understanding of the effects of toxic chemical mixtures on health.

Alex G Stewart, Joy Carter

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental geochemistry and health, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alex G StewartCheshire and Merseyside Health Protection Unit, Microbiology Laboratory, Countess of Chester Health Park, London Road, Chester CH12UL, UK. alex.stewart@hpa.org.uk
Joy Carter

Funding

Biotechnology and Biological Sciences Research CouncilMedical Research Council
6 · The paper itself

Abstract

Mixtures can be divided into simple (chemicals with comparable properties--health risk assessments on the chemicals) and complex, which can be further subdivided into defined (a reasonably distinct composition, created at a specific time and place despite dissimilar components--risk assessments on the common source) and coincidental (chemicals without similar properties or constant composition in time or space-risk assessments on the receptor). Interactions recognized are: independent action, dose addition (additivity), and potentiation (synergy and antagonism). Unpredicted outcomes need recognition. New approaches in higher education and multidisciplinary investigations are essential. The community of the Society for Environmental Geochemistry and Health should help clarify points such as when transformations in mixtures may become important enough to alter the classification and the risk assessment. The multidisciplinary community is also well placed to support the integration of non-chemical influences into mixture analysis and to contribute to the investigation of cumulative and multiple exposures.

Indexed as

Environmental HealthChemistryComplex MixturesEnvironmental PollutantsGeologyHumansInterdisciplinary CommunicationRisk AssessmentToxicologyComplex MixturesEnvironmental Pollutants

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.