ArticleJournal of materials science. Materials in medicine2009
Glass-ceramic scaffolds containing silica mesophases for bone grafting and drug delivery.
Article in Journal of materials science. Materials in medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The trial behind it
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Who cites it
8 citing papers in PubMed.
- Fabricating oxygen self-supplying 3D printed bioactive hydrogel scaffold for augmented vascularized bone regeneration.Bioactive materials · 2024Article
- 3D printed polycaprolactone/gelatin/ordered mesoporous calcium magnesium silicate nanocomposite scaffold for bone tissue regeneration.Journal of materials science. Materials in medicine · 2024Article
- Interaction of alginate with nano-hydroxyapatite-collagen using strontium provides suitable osteogenic platform.Journal of nanobiotechnology · 2022Article
- Hydrophilic and Hydrophobic Mesoporous Silica Derived from Rice Husk Ash as a Potential Drug Carrier.Materials (Basel, Switzerland) · 2018Article
- Composite Biomaterials Based on Sol-Gel Mesoporous Silicate Glasses: A Review.Bioengineering (Basel, Switzerland) · 2017Review
- Uniform Surface Modification of 3D Bioglass(®)-Based Scaffolds with Mesoporous Silica Particles (MCM-41) for Enhancing Drug Delivery Capability.Frontiers in bioengineering and biotechnology · 2015Article
- A New Highly Bioactive Composite for Scaffold Applications: A Feasibility Study.Materials (Basel, Switzerland) · 2011Article
- Self-assembled particles of N-phthaloylchitosan-g-polycaprolactone molecular bottle brushes as carriers for controlled release of indometacin.Journal of materials science. Materials in medicine · 2010Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glass-ceramic macroporous scaffolds were prepared using glass powders and polyethylene (PE) particles of two different sizes. The starting glass, named as Fa-GC, belongs to the system SiO(2)-P(2)O(5)-CaO-MgO-Na(2)O-K(2)O-CaF(2) and was synthesized by a traditional melting-quenching route. The glass was ground and sieved to obtain powders of specific size which were mixed with PE particles and then uniaxially pressed in order to obtain crack-free green samples. The compact of powders underwent a thermal treatment to remove the organic phase and to sinter the Fa-GC powders. Fa-GC scaffolds were characterized by means of X-Ray Diffraction, morphological observations, density measurements, image analysis, mechanical tests and in vitro tests. Composite systems were then prepared combining the drug uptake-delivery properties of MCM-41 silica micro/nanospheres with the Fa-GC scaffold. The system was prepared by soaking the scaffold into the MCM-41 synthesis batch. The composite scaffolds were characterized by means of X-Ray Diffraction, morphological observations, mechanical tests and in vitro tests. Ibuprofen was used as model drug for the uptake and delivery analysis of the composite system. In comparison with the MCM-41-free scaffold, both the adsorption capacity and the drug delivery behaviour were deeply affected by the presence of MCM-41 spheres inside the scaffold.
Indexed as
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Registered trials
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