ArticleMethods in molecular biology (Clifton, N.J.)2009
Analysis of viral and cellular proteins in HIV-1 reverse transcription complexes by co-immunoprecipitation.
Article in Methods in molecular biology (Clifton, N.J.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses.PLoS pathogens · 2021Article
- Identification of a methylated oligoribonucleotide as a potent inhibitor of HIV-1 reverse transcription complex.Nucleic acids research · 2011Article
- Subtype-associated differences in HIV-1 reverse transcription affect the viral replication.Retrovirology · 2010Article
- Implications of the nucleocapsid and the microenvironment in retroviral reverse transcription.Viruses · 2010Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Molecular details and temporal organization of the early (preintegration) phase of HIV life cycle remain among the least investigated and most controversial problems in the biology of HIV. To accomplish reverse transcription and intracellular transport of the viral genetic material, HIV forms multi-molecular complexes termed reverse transcription complexes (RTCs). Analysis of the kinetics of reverse transcription and nuclear import of RTCs, as well as assessment of the changes in their protein content in the course of reverse transcription and nuclear translocation is a necessary step in understanding the mechanisms of cytoplasmic maturation and nuclear import of HIV-1 RTCs. Here, we review methods that allow quantitative assessment of the dynamics of the maturation of HIV-1 RTCs and transformations of RTC protein composition associated with nuclear import of the complexes.
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