ArticleInfection2008
Clinical and laboratory signs as dengue markers during an outbreak in Rio de Janeiro.
Article in Infection, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of Allergic Symptoms with Dengue Infection and Severity: A Systematic Review and Meta-analysis.Virologica Sinica · 2020Pooled it
- Prevalence of chronic comorbidities in dengue fever and West Nile virus: A systematic review and meta-analysis.PloS one · 2018Pooled it
- Global prevalence and risk factors of fatigue and post-infectious fatigue among patients with dengue: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Epidemiological and genetic aspects of the largest dengue outbreak recorded in 2015 in Southeastern Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2021Article
- Clinical and laboratory features that discriminate dengue from other febrile illnesses: a diagnostic accuracy study in Rio de Janeiro, Brazil.BMC infectious diseases · 2013Article
- The clinical differences between dengue and scrub typhus with acute respiratory failure in southern Taiwan.Infection · 2012Article
- Simple Prognostic Criteria can Definitively Identify Patients who Develop Severe Versus Non-Severe Dengue Disease, or Have Other Febrile Illnesses.Journal of clinical medicine research · 2012Article
- Interobserver agreement on signs and symptoms of patients with acute febrile illness.Infection · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOne of the main challenges for clinical research in dengue is the low validity of clinical diagnosis.
objectiveTo analyze clinical and laboratory data as predicitve factors of dengue diagnosis at Evandro Chagas Clinical Research Institute, Oswaldo Cruz Foundation, during the 2001-2002 dengue outbreak in Rio de Janeiro.
methodsCross sectional study comparing clinical laboratory data collected from the National Information System for Compulsory Notification Diseases (SINAN) in two serologically confirmed groups: dengue D (N = 453) and non-dengue ND (N = 80).
resultsFever, exanthema, itching, mean platelet count < 150,000, WBC count < 4,000 and absence of vomiting and of abdominal pain help to distinguish D from ND groups. When considered individually, these signs and symptoms enhance diagnostic sensitivity and, when used in combination, improve specificity.
conclusionA combination of symptoms not necessarily considered indicative of dengue diagnosis could improve surveillance and medical decision-making in simple clinical settings.
Indexed as
Identifiers
19020803What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.