Evidence map›Paper›PMID 19019405›Full record

ReviewVirology2009

Insights into adenovirus host cell interactions from structural studies.

G R Nemerow, L Pache, V Reddy, P L Stewart

Abstract readReview
In one paragraph

Review in Virology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Biological features of fowl adenovirus serotype-4.Frontiers in cellular and infection microbiology · 2024
    Review
  6. Article
  7. The Art of Viral Membrane Fusion and Penetration.Sub-cellular biochemistry · 2023
    Article
  8. Review
  9. Human Adenovirus Associated Hepatic Injury.Frontiers in public health · 2022
    Review
  10. Review
  11. Review
  12. Beyond cancer cells: Targeting the tumor microenvironment with gene therapy and armed oncolytic virus.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

G R NemerowThe Scripps Research Institute, La Jolla, California, 92037, USA. gnemerow@scripps.edu
L Pache
V Reddy
P L Stewart

Funding

AV INTEGRINS AND ADENOVIRUS INTERNALIZATIONR01HL054352 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI NEMEROW, GLEN R · 1995 to 2016
$7.5M
ROLE OF CELL INTEGRINS IN ADENOVIRAL CONJUNCTIVITISR01EY011431 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI NEMEROW, GLEN R · 1997 to 2012
$4.9M
Cryo-EM Structural Studies of Adenovirus Cell EntryR01AI042929 · NIAID · VANDERBILT UNIVERSITY · PI STEWART, PHOEBE L · 2004 to 2010
$2.8M
CRYO-EM STRUCTURAL STUDIES OF ADENOVIRUS CELL ENTRYR29AI042929 · NIAID · VANDERBILT UNIVERSITY · PI STEWART, PHOEBE L · 1997 to 2001
$214k
NEI NIH HHS EY011431NEI NIH HHS R01 EY011431NHLBI NIH HHS HL054352NHLBI NIH HHS R01 HL054352NIAID NIH HHS AI42929NIAID NIH HHS R01 AI042929NIAID NIH HHS R29 AI042929
6 · The paper itself

Abstract

Human adenoviruses cause a significant number of acute respiratory, enteric and ocular infections, however they have also served as useful model systems for uncovering fundamental aspects of cell and molecular biology. In addition, replication-defective forms of adenovirus are being used in gene transfer and vaccine clinical trials. Over the past decade, steady advances in structural biology techniques have helped reveal important insights into the earliest events in the adenovirus life cycle as well as virus interactions with components of the host immune system. This review highlights the continuing use of structure-based approaches to uncover the molecular features of adenovirus-host interactions.

Indexed as

Host-Pathogen InteractionsAdenoviruses, HumanAdenovirus Infections, HumanCapsid ProteinsHumansImmunologic FactorsIntegrinsMembrane Cofactor ProteinSialic AcidsCapsid Proteinshexon capsid protein, AdenovirusImmunologic FactorsIntegrinsMembrane Cofactor Proteinpenton protein, adenovirusSialic Acids

Identifiers

PMID19019405
PMCPMC2666334

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.