ArticleMicrobial cell factories2008
Engineering and Applications of fungal laccases for organic synthesis.
Article in Microbial cell factories, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed, 331 citations in OpenAlex.
- De novo biosynthesis of plant lignans by synthetic yeast consortia.Nature chemical biology · 2025Article
- Proteins from Edible Mushrooms: Nutritional Role and Contribution to Well-Being.Foods (Basel, Switzerland) · 2025Review
- Production of laccase enzyme from Curvularia lunata MY3: purification and characterization.Folia microbiologica · 2024Article
- Fungal Laccases: Fundamentals, Engineering and Classification Update.Biomolecules · 2023Review
- The Biomodified Lignin Platform: A Review.Polymers · 2023Review
- Potential of the enzyme laccase for the synthesis and derivatization of antimicrobial compounds.World journal of microbiology & biotechnology · 2023Review
- Medical Use of Polycatecholamines + Oxidoreductases-Modified Curdlan Hydrogels-Perspectives.International journal of molecular sciences · 2022Article
- A Brief History of Colour, the Environmental Impact of Synthetic Dyes and Removal by Using Laccases.Molecules (Basel, Switzerland) · 2021Review
- Laccases: Versatile Biocatalysts for the Synthesis of Heterocyclic Cores.Molecules (Basel, Switzerland) · 2021Review
- Enzymatic treatment of phenolic pollutants by a small laccase immobilized on APTES-functionalised magnetic nanoparticles.3 Biotech · 2021Article
- Heterologous Expression, Engineering and Characterization of a Novel Laccase ofJournal of fungi (Basel, Switzerland) · 2021Article
- Structural analysis and biochemical properties of laccase enzymes from two Pediococcus species.Microbial biotechnology · 2021Article
- Design of an improved universal signal peptide based on the α-factor mating secretion signal for enzyme production in yeast.Cellular and molecular life sciences : CMLS · 2021Article
- Status of the application of exogenous enzyme technology for the development of natural plant resources.Bioprocess and biosystems engineering · 2021Review
- Ring-Closure Mechanisms Mediated by Laccase to Synthesize Phenothiazines, Phenoxazines, and Phenazines.ACS omega · 2020Article
- Lignin-Based Pesticide Delivery System.ACS omega · 2020Article
- Ligninolytic enzymes and its mechanisms for degradation of lignocellulosic waste in environment.Heliyon · 2020Review
- Efficient and sustainable laccase-catalyzed iodination ofRSC advances · 2019Article
- Synthesizing Polyaniline With Laccase/OFrontiers in bioengineering and biotechnology · 2019Review
- Synthesis of Dextran-Phenoxodiol and Evaluation of Its Physical Stability and Biological Activity.Frontiers in bioengineering and biotechnology · 2019Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laccases are multi-copper containing oxidases (EC 1.10.3.2), widely distributed in fungi, higher plants and bacteria. Laccase catalyses the oxidation of phenols, polyphenols and anilines by one-electron abstraction, with the concomitant reduction of oxygen to water in a four-electron transfer process. In the presence of small redox mediators, laccase offers a broader repertory of oxidations including non-phenolic substrates. Hence, fungal laccases are considered as ideal green catalysts of great biotechnological impact due to their few requirements (they only require air, and they produce water as the only by-product) and their broad substrate specificity, including direct bioelectrocatalysis.Thus, laccases and/or laccase-mediator systems find potential applications in bioremediation, paper pulp bleaching, finishing of textiles, bio-fuel cells and more. Significantly, laccases can be used in organic synthesis, as they can perform exquisite transformations ranging from the oxidation of functional groups to the heteromolecular coupling for production of new antibiotics derivatives, or the catalysis of key steps in the synthesis of complex natural products. In this review, the application of fungal laccases and their engineering by rational design and directed evolution for organic synthesis purposes are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.