Evidence map›Paper›PMID 19018697›Full record

ArticleStem cells and development

Cord blood stem cell therapy for acquired immune deficiency syndrome.

Gabriel Gonzalez, Elizabeth J Shpall, Joseph C Gathe, Richard R Behringer

Abstract read
In one paragraph

Article in Stem cells and development. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gabriel GonzalezDepartment of Genetics, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
Elizabeth J Shpall
Joseph C Gathe
Richard R Behringer
The University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cord blood stem cell transplantation is routinely used to treat hematopoietic diseases. Individuals who are homozygous for the 32 polymorphism of the CCR5 locus, encoding a co-receptor for HIV-1, are normal and are resistant to HIV infection. Here we suggest that public cord blood repositories are likely to contain CCR5 homozygous units that could be used as a therapy for HIV-infected individuals.

Indexed as

Cord Blood Stem Cell TransplantationAcquired Immunodeficiency SyndromeCell- and Tissue-Based TherapyFetal BloodHematopoietic Stem CellsHIV-1HumansPolymorphism, GeneticReceptors, CCR5Receptors, CCR5

Identifiers

PMID19018697
PMCPMC3141738
OpenAlexW2080644015

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.