ArticlePediatrics2008
Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR): background commentary of RIVUR investigators.
Article in Pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00405704 (Randomized Intervention for Children With Vesicoureteral Reflux), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR)
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Long-term antibiotics for preventing recurrent urinary tract infection in children.The Cochrane database of systematic reviews · 2019Pooled it
- Interventions for primary vesicoureteric reflux.The Cochrane database of systematic reviews · 2019Pooled it
- Antimicrobial prophylaxis for children with vesicoureteral reflux.The New England journal of medicine · 2014Trial
- The RIVUR trial: profile and baseline clinical associations of children with vesicoureteral reflux.Pediatrics · 2013Trial
- Urinary tract infections in children.Nature reviews. Urology · 2026Review
- Efficacy of hc-tNGS for pathogen identification for pediatric cUTIs: a real-world observational study.Frontiers in cellular and infection microbiology · 2026Observational
- Culture-positive urinary tract infection following micturating cystourethrogram in children.Asian journal of urology · 2022Article
- Reduced urinary excretion of neutrophil gelatinase-associated lipocalin as a risk factor for recurrence of febrile urinary tract infection in children.Pediatric nephrology (Berlin, Germany) · 2021Article
- [Long-term prognosis of vesicoureteral reflux: a follow-up observation of 138 children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019Article
- Urinary C-megalin for screening of renal scarring in children after febrile urinary tract infection.Pediatric research · 2018Article
- The diagnosis, evaluation and treatment of acute and recurrent pediatric urinary tract infections.Expert review of anti-infective therapy · 2015Review
- The innate immune response during urinary tract infection and pyelonephritis.Pediatric nephrology (Berlin, Germany) · 2014Review
- Incidence of abnormal imaging and recurrent pyelonephritis after first febrile urinary tract infection in children 2 to 24 months old.The Journal of urology · 2013Article
- The accuracy and health risks of a voiding cystourethrogram after a febrile urinary tract infection.Journal of pediatric urology · 2012Article
- Febrile urinary tract infection, vesicoureteral reflux, and renal scarring: current controversies in approach to evaluation.Pediatric surgery international · 2011Review
- Pediatric urinary tract infections: an analysis of hospitalizations, charges, and costs in the USA.Pediatric nephrology (Berlin, Germany) · 2010Article
- Urinary tract infections in children: recommendations for antibiotic prophylaxis and evaluation. An evidence-based approach.Current urology reports · 2010Review
- Diagnosis and management of vesicoureteral reflux in children.Nature reviews. Urology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 9 institutions in 1 country.
Funding
Abstract
Because of the frequency of urinary tract infections in children, off-label use of antimicrobial prophylaxis is often the usual treatment of children with vesicoureteral reflux, and such use is increasingly being called into question; hence, a definitive study to determine the value of antimicrobial prophylaxis with regard to the recurrence of urinary tract infection and the incidence of renal scarring is essential. The currently recommended follow-up procedures (repeated urine cultures, renal and genitourinary imaging, antimicrobial therapy and prophylaxis, as well as other factors including cleanliness, adequate bladder and bowel emptying, and compliance with protocols) are expensive (in terms of time, attention to detail, and cost) and cumbersome. Such recommendations should be evidence-based.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.