ArticleProceedings of the National Academy of Sciences of the United States of America2008
Transcriptome analysis and identification of regulators for long-term plasticity in Aplysia kurodai.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Endogenous l- to d-amino acid residue isomerization modulates selectivity between distinct neuropeptide receptor family members.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Transcriptional correlates of memory maintenance following long-term sensitization ofLearning & memory (Cold Spring Harbor, N.Y.) · 2017Article
- Identification of genes related to learning and memory in the brain transcriptome of the mollusc, Hermissenda crassicornis.Learning & memory (Cold Spring Harbor, N.Y.) · 2015Article
- Characterization of the rapid transcriptional response to long-term sensitization training in Aplysia californica.Neurobiology of learning and memory · 2014Article
- Transcriptional analysis of a whole-body form of long-term habituation in Aplysia californica.Learning & memory (Cold Spring Harbor, N.Y.) · 2014Article
- The plasticity of the grapevine berry transcriptome.Genome biology · 2013Article
- AU-rich element-binding protein negatively regulates CCAAT enhancer-binding protein mRNA stability during long-term synaptic plasticity in Aplysia.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Transcriptional changes following long-term sensitization training and in vivo serotonin exposure in Aplysia californica.PloS one · 2012Article
- Parallel evolution of nitric oxide signaling: diversity of synthesis and memory pathways.Frontiers in bioscience (Landmark edition) · 2011Review
- Queen conch (Strombus gigas) testis regresses during the reproductive season at nearshore sites in the Florida Keys.PloS one · 2010Article
- Sensory sea slugs: Towards decoding the molecular toolkit required for a mollusc to smell.Communicative & integrative biology · 2010Article
- Differential evolutionary rates of neuronal transcriptome in Aplysia kurodai and Aplysia californica as a tool for gene mining.Journal of neurogenetics · 2010Article
- Construction of a medicinal leech transcriptome database and its application to the identification of leech homologs of neural and innate immune genes.BMC genomics · 2010Article
- The transcriptome of the early life history stages of the California Sea Hare Aplysia californica.Comparative biochemistry and physiology. Part D, Genomics & proteomics · 2010Article
- Identification of a serotonin receptor coupled to adenylyl cyclase involved in learning-related heterosynaptic facilitation in Aplysia.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Transcriptome and protein domain analyses in Aplysia nervous system with evolutionary implications.Communicative & integrative biology · 2009Article
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Corrections and comments
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Authors and funding
18 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The marine mollusk Aplysia is a useful model organism for studying the cellular bases of behavior and plasticity. However, molecular studies of Aplysia have been limited by the lack of genomic information. Recently, a large scale characterization of neuronal transcripts was performed in A. californica. Here, we report the analysis of a parallel set of neuronal transcripts from a closely related species A. kurodai found in the northwestern Pacific. We collected 4,859 nonredundant sequences from the nervous system tissue of A. kurodai. By performing microarray and real-time PCR analyses, we found that ApC/EBP, matrilin, antistasin, and eIF3e clones were significantly up-regulated and a BAT1 homologous clone was significantly down-regulated by 5-HT treatment. Among these, we further demonstrated that the Ap-eIF3e plays a key role in 5-HT-induced long-term facilitation (LTF) as a positive regulator.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.