ArticleProceedings of the National Academy of Sciences of the United States of America2008
Metagenomic analysis indicates that stressors induce production of herpes-like viruses in the coral Porites compressa.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
88 citing papers in PubMed, 1 synthesis or guideline pooled it, 208 citations in OpenAlex.
- The GAAS metagenomic tool and its estimations of viral and microbial average genome size in four major biomes.PLoS computational biology · 2009Pooled it
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- Microbial Communities and their Functional Role Associated with the Localised Outbreak of Coral Growth Anomalies in Eastern Arabian Sea.Indian journal of microbiology · 2025Article
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- Physiological and microbiome adaptation of coralEcology and evolution · 2024Article
- Globally distributed bacteriophage genomes reveal mechanisms of tripartite phage-bacteria-coral interactions.The ISME journal · 2024Article
- Coral mucus as a reservoir of bacteriophages targeting Vibrio pathogens.The ISME journal · 2024Article
- Lytic/Lysogenic Transition as a Life-History Switch.Virus evolution · 2024Article
- Filamentous virus-like particles are present in coral dinoflagellates across genera and ocean basins.The ISME journal · 2023Article
- Viruses of a key coral symbiont exhibit temperature-driven productivity across a reefscape.ISME communications · 2023Article
- The coral microbiome: towards an understanding of the molecular mechanisms of coral-microbiota interactions.FEMS microbiology reviews · 2023Article
- Freshwater Mussels Show Elevated Viral Richness and Intensity during a Mortality Event.Viruses · 2022Article
- Thermal stress triggers productive viral infection of a key coral reef symbiont.The ISME journal · 2022Article
- Revisiting the rules of life for viruses of microorganisms.Nature reviews. Microbiology · 2021Review
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- An Unconventional Flavivirus and Other RNA Viruses in the Sea Cucumber (Holothuroidea; Echinodermata) Virome.Viruses · 2020Article
- Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During the last several decades corals have been in decline and at least one-third of all coral species are now threatened with extinction. Coral disease has been a major contributor to this threat, but little is known about the responsible pathogens. To date most research has focused on bacterial and fungal diseases; however, viruses may also be important for coral health. Using a combination of empirical viral metagenomics and real-time PCR, we show that Porites compressa corals contain a suite of eukaryotic viruses, many related to the Herpesviridae. This coral-associated viral consortium was found to shift in response to abiotic stressors. In particular, when exposed to reduced pH, elevated nutrients, and thermal stress, the abundance of herpes-like viral sequences rapidly increased in 2 separate experiments. Herpes-like viral sequences were rarely detected in apparently healthy corals, but were abundant in a majority of stressed samples. In addition, surveys of the Nematostella and Hydra genomic projects demonstrate that even distantly related Cnidarians contain numerous herpes-like viral genes, likely as a result of latent or endogenous viral infection. These data support the hypotheses that corals experience viral infections, which are exacerbated by stress, and that herpes-like viruses are common in Cnidarians.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.