Evidence map›Paper›PMID 19017696›Full record

ArticleOccupational and environmental medicine2009

Degreasing and risk of non-Hodgkin lymphoma.

M P Purdue, R K Severson, J S Colt, P Stewart, A J De Roos, J R Cerhan, W Cozen, S Davis, P Hartge, M Schenk and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Occupational and environmental medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M P PurdueOccupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS 8114, 6120 Executive Blvd, Bethesda, MD 20892, USA. purduem@mail.nih.gov
R K Severson
J S Colt
P Stewart
A J De Roos
J R Cerhan
W Cozen
S Davis
P Hartge
M Schenk
A Blair

Funding

Molecular Epidemiology Studies of Occupational and Environmental ExposuresZIACP010121 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ROTHMAN, NATHANIEL · 2009 to 2025
$23.5M
Multidisciplinary Studies of LymphomaZIACP010170 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI MORTON, LINDSAY · 2009 to 2025
$10.7M
SURVEILLANCE, EPIDEMIOLOGY, AND END RESULTS--SEERN01PC065064 · PC · WAYNE STATE UNIVERSITY · PI SCHWARTZ, ANN G · 1996 to 2000
$4.5M
SURVEILLANCE EPIDEMIOLOGY &END RESULTS PROGRAMN01PC067009 · PC · FRED HUTCHINSON CANCER RESEARCH CENTER · PI THOMAS, DAVID B · 1996 to 2000
$3.0M
Intramural NIH HHS ZIA CP010170NCI NIH HHS N01-CN-67008NCI NIH HHS N01-CN-67010NCI NIH HHS N01 PC065064NCI NIH HHS N01 PC067009NCI NIH HHS N01-PC-67009
6 · The paper itself

Abstract

objectiveTo investigate the relationship between selected solvent-related workplace tasks (degreasing, painting, gluing, stripping paint, staining) and risk of non-Hodgkin lymphoma (NHL).

methodsWe analysed occupational data from a large population-based case-control study of NHL conducted in the USA. For participants reporting occupations with possible exposure to organic solvents, job-specific interview modules were administered to elicit in-depth information on solvent-related workplace tasks and other exposure-related factors (225 cases, 189 controls). Unconditional logistic regression models were fit to calculate odds ratios (ORs) and 95% CI for average frequency, maximal frequency and cumulative number of hours having performed each task. Individuals with jobs rated as unexposed to organic solvents in the workplace (180 cases, 213 controls) were used as a reference group.

resultsWe observed an increased risk of NHL among subjects in the highest category of maximal degreasing frequency (>520 h/year: OR 2.1, 95% CI 0.9 to 4.9, trend test p = 0.02). We found similar associations for the highest levels of average frequency and, among men, cumulative number of hours. Other solvent-related tasks were not associated with NHL.

conclusionFindings from this case-control analysis of solvent-related tasks suggest that frequent degreasing work may be associated with an elevated risk of NHL.

Indexed as

AgedCase-Control StudiesFemaleHumansLymphoma, Non-HodgkinMaleMiddle AgedOccupational DiseasesOccupational ExposureSolventsUnited StatesSolvents

Identifiers

PMID19017696
PMCPMC2995288

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.