Evidence map›Paper›PMID 1901653›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1991

An idiotypic network model of AIDS immunopathogenesis.

G W Hoffmann, T A Kion, M D Grant

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
17.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 84 citations in OpenAlex.

  1. T-Cell Receptor Sequences Identify Combined Coxsackievirus-International journal of molecular sciences · 2024
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  8. The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection.Proceedings of the National Academy of Sciences of the United States of America · 1994
    Article
  9. Article
  10. Review
  11. Mechanism for the T4 lymphopenia of AIDS.Proceedings of the National Academy of Sciences of the United States of America · 1993
    Article
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  18. Looking beyond the numbers.Integrative physiological and behavioral science : the official journal of the Pavlovian Society
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

G W HoffmannDepartment of Microbiology, University of British Columbia, Vancouver, Canada.
T A Kion
M D Grant
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considerations from a network theory of the immune system suggest that human immunodeficiency virus and allogeneic stimuli may act synergistically to cause AIDS. The immune responses to these stimuli include two components that are directed against each other. In some AIDS risk groups other antigens that mimic major histocompatibility complex antigens may substitute for allogeneic stimuli. Implications for the prevention of AIDS are discussed.

Indexed as

Acquired Immunodeficiency SyndromeAfricaAnimalsAntigens, Differentiation, T-LymphocyteAutoantibodiesAutoimmune DiseasesCD4 AntigensCD8 AntigensCollagenHemophilia AHIVHIV AntigensHIV Envelope Protein gp120HLA-D AntigensHomosexualityHumansAntigens, Differentiation, T-LymphocyteAutoantibodiesCD4 AntigensCD8 AntigensCollagenHIV AntigensHIV Envelope Protein gp120HLA-D AntigensImmunoglobulin IdiotypesIsoantibodiesIsoantigens

Identifiers

PMID1901653
PMCPMC51384
OpenAlexW2126350898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.