Evidence map›Paper›PMID 19014824›Full record

ArticleThe Journal of pediatrics2008

Enteral feeding in prostaglandin-dependent neonates: is it a safe practice?

Lisa Willis, Patti Thureen, Jonathan Kaufman, Erica Wymore, Heather Skillman, Eduardo da Cruz

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in The Journal of pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01475357 (Intestinal Function in Neonates With Complex Congenital Heart Disease), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01475357 nacompletednot on this mapstarted 2011, after this paper: background citation

Intestinal Function in Neonates With Complex Congenital Heart Disease

TypeinterventionalSponsorMedical University of South CarolinaRan2011 to 2014Enrolled27ConditionsCongenital Heart Defects, Growth FailureArmsArm 1: NPO by mouth pre-operative, Arm 2: Fresh Breast Milk pre-operative
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Review
  5. Review
  6. Review
  7. Feeding Approach to Optimizing Nutrition in Infants with Congenital Heart Disease.Journal of cardiovascular development and disease · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. A preoperative standardized feeding protocol improves human milk use in infants with complex congenital heart disease.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Preoperative Feeding Neonates With Cardiac Disease.World journal for pediatric & congenital heart surgery · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lisa WillisHeart Institute, The Children's Hospital of Denver, University of Colorado at Denver & Health Sciences Center, Denver, CO, USA.
Patti Thureen
Jonathan Kaufman
Erica Wymore
Heather Skillman
Eduardo da Cruz
Children's Hospital Colorado · USUniversity of Colorado Denver · USUniversity of Denver · US

Funding

Training Program in Perinatal Biology and MedicineT32HD007186 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Paul Joseph Rozance · 1985 to 2026
$6.5M
NICHD NIH HHS T32 HD007186
6 · The paper itself

Abstract

In many centers presurgical term neonates with prostaglandin-dependent cardiac lesions experience nutritional deficiency because of postponed enteral feeds. We recently adopted early enteral feeding in these infants. This retrospective study demonstrates feeding tolerance in 33 of 34 neonates fed enterally while receiving prostaglandin, suggesting the safety of this practice.

Indexed as

Preoperative CareAlprostadilEnteral NutritionEnterocolitis, NecrotizingFemaleHeart Defects, CongenitalHumansInfant, NewbornIntensive Care UnitsMaleRetrospective StudiesVasodilator AgentsAlprostadilVasodilator Agents

Identifiers

PMID19014824
PMCPMC2714666
OpenAlexW1996389204

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.