Evidence map›Paper›PMID 19014773›Full record

Trial reportThe Journal of allergy and clinical immunology2008

Administration of oral vitamin D induces cathelicidin production in atopic individuals.

Tissa R Hata, Paul Kotol, Michelle Jackson, Meggie Nguyen, Aimee Paik, Don Udall, Kimi Kanada, Kenshi Yamasaki, Doru Alexandrescu, Richard L Gallo

Registry-linked trialOpen access · greenAbstract readClinical TrialLetter
In one paragraph

Trial report in The Journal of allergy and clinical immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01838447 (Prevention of Post-Cardiac Surgery Vitamin D Deficiency in Children With Congenital Heart Disease), which is not on this map. Cited by 80 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 2 pooled it
19.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01838447 phase2completednot on this mapstarted 2013, after this paper: background citation

Prevention of Post-Cardiac Surgery Vitamin D Deficiency in Children With Congenital Heart Disease: A Pilot Dose Evaluation Randomized Controlled Trial

TypeinterventionalSponsorChildren's Hospital of Eastern OntarioRan2013 to 2015Enrolled46ConditionsVitamin D Deficiency, Thoracic Surgery, Pediatric Disorders, Heart Defects, CongenitalArmsCholecalciferol
3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 2 syntheses or guidelines pooled it, 254 citations in OpenAlex.

  1. Pooled it
  2. Dietary supplements for established atopic eczema.The Cochrane database of systematic reviews · 2012
    Pooled it
  3. Trial
  4. Impact of high-dose vitamin DNutrition (Burbank, Los Angeles County, Calif.) · 2017
    Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. A randomized controlled trial on the effect of vitamin D3 on inflammation and cathelicidin gene expression in ulcerative colitis patients.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Trial
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Tissa R HataDivision of Dermatology, University of California San Diego, La Jolla, Calif. Electronic address: thata@ucsd.edu.
Paul KotolDivision of Dermatology, University of California San Diego, La Jolla, Calif.
Michelle JacksonDivision of Dermatology, University of California San Diego, La Jolla, Calif.
Meggie NguyenDivision of Dermatology, University of California San Diego, La Jolla, Calif.
Aimee PaikDivision of Dermatology, University of California San Diego, La Jolla, Calif.
Don UdallDivision of Dermatology, University of California San Diego, La Jolla, Calif.
Kimi KanadaDivision of Dermatology, University of California San Diego, La Jolla, Calif.
Kenshi YamasakiDivision of Dermatology, University of California San Diego, La Jolla, Calif.
Doru AlexandrescuDivision of Dermatology, University of California San Diego, La Jolla, Calif.
Richard L GalloDivision of Dermatology, University of California San Diego, La Jolla, Calif.
University of California, San Diego · US

Funding

Cathelicidins in Skin ImmunityR01AI052453 · NIAID · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI GALLO, RICHARD L, NIZET, VICTOR · 2002 to 2017
$5.3M
Cathelicidin in Skin ImmunityR37AI052453 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard L Gallo, Victor Nizet · 2019 to 2026
$4.6M
Proteolysis and Skin AntimicrobialsR01AR052728 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI GALLO, RICHARD L · 2006 to 2015
$3.3M
NIAID NIH HHS R01 AI052453NIAID NIH HHS R37 AI052453NIAMS NIH HHS R01 AR052728
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, OralAntimicrobial Cationic PeptidesCathelicidinsDermatitis, AtopicFemaleGene Expression RegulationHumansMaleVitamin DVitaminsAntimicrobial Cationic PeptidesCathelicidinsVitamin DVitamins

Identifiers

PMID19014773
PMCPMC2659525
OpenAlexW2107811099

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.