ArticleEnvironmental health : a global access science source2008
Semen quality in Peruvian pesticide applicators: association between urinary organophosphate metabolites and semen parameters.
Article in Environmental health : a global access science source, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Adult Organophosphate and Carbamate Insecticide Exposure and Sperm Concentration: A Systematic Review and Meta-Analysis of the Epidemiological Evidence.Environmental health perspectives · 2023Pooled it
- Impact of organophosphate pesticides exposure on human semen parameters and testosterone: a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- The environmental and occupational influence of pesticides on male fertility: A systematic review of human studies.Andrology · 2022Pooled it
- A systematic review of the influence of occupational organophosphate pesticides exposure on neurological impairment.BMJ open · 2014Pooled it
- Environmental and occupational pesticide exposure and human sperm parameters: a systematic review.Toxicology · 2013Pooled it
- Photocatalytic Degradation of Profenofos Using ZnO Nanoparticles Biosynthesized with Aqueous Grape Seed Extract.Molecules (Basel, Switzerland) · 2026Article
- Association of exposure to organophosphate pesticides with reproductive lifespan.BMC women's health · 2026Article
- Ecological and reproductive consequences of endocrine-disrupting chemicals in agricultural systems.Reproduction & fertility · 2026Review
- Organophosphate Pesticide Exposure and Semen Quality in Healthy Young Men: A Pilot Study.Antioxidants (Basel, Switzerland) · 2025Article
- The impact, mechanisms and prevention strategies of environmental endocrine disruptors on male reproductive health.Frontiers in endocrinology · 2025Review
- Dietary Exposure to Pesticide and Veterinary Drug Residues and Their Effects on Human Fertility and Embryo Development: A Global Overview.International journal of molecular sciences · 2024Review
- Endocrine-disrupting chemicals: Mainstream recognition of health effects and implications for the practicing internist.Journal of internal medicine · 2024Article
- Determination of biochemical and histopathological changes on testicular and epididymis tissues induced by exposure to insecticide Imidacloprid during postnatal development in rats.BMC pharmacology & toxicology · 2023Article
- Health Effects of Pesticide Exposure in Latin American and the Caribbean Populations: A Scoping Review.Environmental health perspectives · 2022Article
- Assessment of Organophosphate Pesticides Exposure in Men with Idiopathic Abnormal Semen Analysis: A Cross-Sectional Pilot Study.International journal of fertility & sterility · 2021Article
- Reproductive Health Risks Associated with Occupational and Environmental Exposure to Pesticides.International journal of environmental research and public health · 2021Review
- Endocrine-disrupting chemicals: implications for human health.The lancet. Diabetes & endocrinology · 2020Review
- More pesticides-less children?Wiener klinische Wochenschrift · 2020Article
- Low dose of flurochloridone affected reproductive system of male rats but not fertility and early embryonic development.Reproductive biology and endocrinology : RB&E · 2019Article
- Pesticide interactions and risks of sperm chromosomal abnormalities.International journal of hygiene and environmental health · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundOrganophosphates are broad class of chemicals widely used as pesticides throughout the world. We performed a cross-sectional study of associations between dialkylphosphate metabolites of organophosphates and semen quality among pesticide applicators in Majes (Arequipa), Peru.
methodsThirty-one men exposed to organophosphate (OP) pesticides and 31 non-exposed were recruited (age, 20-60 years). In exposed subjects, semen and a blood sample were obtained one day after the last pesticide application. Subjects were grouped according to levels of OP metabolites in urine. Semen samples were analyzed for sperm concentration, percentage of sperm motility, percentage of normal morphology, semen leucocytes and concentrations of fructose and zinc. Exposure to OP was assessed by measuring six urinary OP metabolites (dimethyl and diethyl phosphates and thiophosphates) by gas chromatography using a single flame photometric detector.
resultsDiethyldithiophosphate (p = 0.04) and diethylthiophosphate (p = 0.02) better reflected occupational pesticide exposure than other OP metabolites. Semen analysis revealed a significant reduction of semen volume and an increase in semen pH in men with OP metabolites. Multiple regression analysis showed that both occupational exposure to pesticides and the time of exposure to pesticides were more closely related to alterations in semen quality parameters than the single measurement of OP metabolites in urine.
conclusionThe study demonstrated that occupational exposure to OP pesticides was more closely related to alterations in semen quality than a single measurement of urine OP metabolites. Current measurement of OP metabolites in urine may not reflect the full risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.